Dynamic MR digital subtraction angiography using contrast enhancement, fast data acquisition, and complex subtraction
Dynamic MR digital subtraction angiography using contrast enhancement, fast data acquisition, and complex subtraction
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DOI：
10.1002/mrm.1910360408
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发表时间：
1996-10-01
影响因子：
3.3
通讯作者：
Ehman, RL
中科院分区：
文献类型：
--
作者：
Wang, Y;Johnston, DL;Ehman, RL
提出了一种采用快速采集、对比度增强和复数减影的动态磁共振血管成像技术--MR数字减影血管成像(MRDSA)，当向患者体内注射对比剂时，开始数据采集，使用快速梯度回波序列动态采集10-100个S的厚片，类似于X光DSA，从没有对比度增强的图像中选择一个掩模，然后从该掩模中减去图像生成血管图像。采用复数减法克服体素中流动磁化与静止磁化的相位差引起的部分体积效应，血管信号是造影剂对血流磁化的增强。28例患者行MRDSA，包括肺、脑、腿、腹部和盆腔的血管，所有靶血管均被MRDSA很好地显示，测量了相应的动态信息(造影剂到达时间t(A)/t(Av)=3.4/4.7S，脑10.3/4.9tv)。12.8/19.3对于主动脉，15.2/12.6 S对于小腿，MR DSA可以以很短的采集时间提供动态血管成像。
A dynamic MR angiography technique, MR digital subtraction angiography (MR DSA), is proposed using fast acquisition, contrast enhancement, and complex subtraction, When a bolus of contrast is injected into a patient, data acquisition begins, dynamically acquiring a thick slab using a fast gradient echo sequence for 10-100 s, Similar to x-ray DSA, a mask is selected from the images without contrast enhancement, and later images are subtracted from the mask to generate angiograms. Complex subtraction is used to overcome the partial volume effects related to the phase difference between the flowing and stationary magnetization in a voxel, Vessel signal is the enhancement of flow magnetization resulting from the contrast bolus, MR DSA was performed in 28 patients, including vessels in the lungs, brains, legs, abdomen, and pelvis, All targeted vessels were well depicted with MR DSA, Corresponding dynamic information (contrast arrival time t(a) and duration of the arterial phase t(av)) was measured: t(a)/t(av) = 3.4/4.7 s for the lung, 10.3/4.9 s for the brain, 12.8/19.3 for the aorta, 15.2/12.6 s for the leg, MR DSA can provide dynamic angiographic images using a very short acquisition time.