Another battle won in the phage-host arms race: Pseudomonas phage blocks quorum sensing regulator LasR.
Another battle won in the phage-host arms race: Pseudomonas phage blocks quorum sensing regulator LasR.
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噬菌体-宿主军备竞赛中的另一场战斗获胜：假单胞菌噬菌体阻断群体感应调节因子 LasR。
DOI：
10.1016/j.molcel.2021.01.007
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发表时间：
2021
期刊：
影响因子：
16
通讯作者：
Mukherjee,Sampriti
中科院分区：
文献类型：
--
作者：
vanKessel,JuliaC;Mukherjee,Sampriti
Shah等人（2021）发现噬菌体编码的蛋白质Aqs1，在感染后立即策略性地阻断铜绿假单胞菌感应受体LasR，以抵消宿主的群体感应程序，这是一种可能在其他细菌中保守的防御策略。
Shah et al. (2021) uncover phage-encoded protein Aqs1 that tactically blocksPseudomonas aeruginosaquorum-sensing receptor LasR immediately upon infection to counteract the host's quorum-sensing program, a defense strategy that is likely conserved in other phages.