Are semantic deficits in schizophrenia due to problems with access or storage?

Are semantic deficits in schizophrenia due to problems with access or storage?
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DOI:
10.1016/j.schres.2005.11.001
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发表时间:
2006-02-28
影响因子:
4.5
通讯作者:
David, AS
David, AS
中科院分区:
医学2区
文献类型:
--
作者:
Rossell, SL;David, AS

文献摘要

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语义加工缺陷是精神分裂症认知异常的核心。这种语义缺陷可能与语义知识的不良访问或不良存储有关。32名精神分裂症患者和32名匹配的正常对照者进行了5项语义加工任务,考察了项目特异性一致性随时间的变化、词频效应和语义启动。一组患者在三个不同的场合执行任务。一般认为,存储赤字是由项目特定的一致性表现,所有夸大的影响,词频,和发生hyperpriming的信号;所有访问赤字是由这些影响的情况下。数据表明,特定项目的一致性,频率效应和显着的超启动。这种模式与精神分裂症患者语义记忆的储存缺陷一致。(c)2005 Elsevier B. V.保留所有权利。
Semantic processing deficits are central to cognitive abnormalities in schizophrenia. Such semantic deficits may be related to either poor access or poor storage of semantic knowledge. 32 schizophrenia patients and 32 matched normal controls performed five semantic processing tasks that examined item-specific consistency over time, the word frequency effect and semantic priming. A subgroup of patients performed tasks on three separate occasions. It is generally assumed that a storage deficit is signalled by item-specific consistent performance, ail exaggerated effect of word frequency, and the occurrence of hyperpriming; ail access deficit is signalled by the absence of these effects. The data demonstrated item-specific consistency, a frequency effect and significant hyperpriming. The pattern is consistent with a storage deficit of semantic memory in schizophrenia. (c) 2005 Elsevier B.V. All rights reserved.