Developmental assessment of preterm infants at 2 years: validity of parent reports

Developmental assessment of preterm infants at 2 years: validity of parent reports
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DOI:
10.1111/j.1469-8749.2007.02010.x
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发表时间:
2008-01-01
影响因子:
3.8
通讯作者:
Marlow, Neil
Marlow, Neil
中科院分区:
医学2区
文献类型:
--
作者:
Johnson, Samantha;Wolke, Dieter;Marlow, Neil

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父母问卷是衡量结果的标准化测试的廉价替代品。儿童能力的父母报告先前已经过修订(PARCA-R),并经验证可用于2岁的极早产儿。这项研究重新验证了PARCA-R在更大且更具包容性的早产儿样本中评估认知的能力。164名儿童(82名男性,82名女性),妊娠< 32周(中位数29周,四分位距[IQR] 28- 30周);中位数出生体重1200 g(IQR 925- 1463 g),使用贝利婴儿发育量表-第2版(BSID-II)的智力发育指数(MDI)在2岁校正年龄进行评估。家长填写PARCA-R问卷。PARCA-R父母报告复合(PRC)评分和MDI评分之间的显著相关性(r=0.77,95%置信区间[CI] 0.69-0.82,p < 0.01)证明了同时有效性。接收器操作特性确定的PRC截止值< 44具有最佳区分能力(曲线下面积0.92),识别MDI < 70,灵敏度为85%(95% CI 0.58-0.96),87%特异性(95% CI 0.81-0.92)、98%阴性预测值(95% CI 0.95-1)和37%阳性预测值(95% CI 0.22-0.54)。PARCA-R在识别2岁时极早产儿认知延迟方面具有良好的同时效度和诊断实用性。它是有用的结果测量,发展筛选,并促进家长参与随访。
Parental questionnaires are inexpensive alternatives to standardized testing for outcome measurement. The Parent Report of Children's Abilities has previously been revised (PARCA-R) and validated for use with very-preterm infants at 2 years of age. This study revalidated the PARCA-R for assessing cognition in a larger and more inclusive sample of preterm infants. One hundred and sixty-four children (82 males, 82 females) of < 32 weeks' gestation (median 29wks, interquartile range [IQR] 28-30wks); and median birthweight 1200g (IQR 925-1463g) were evaluated using the Mental Development Index (MDI) of the Bayley Scales of Infant Development - 2nd edition (BSID-II) at 2 years' corrected age. Parents completed the PARCA-R questionnaire. Significant correlations between PARCA-R Parent Report Composite (PRC) scores and MDI scores (r=0.77, 95% confidence interval [CI] 0.69-0.82, p < 0.01) demonstrated concurrent validity. A receiver operating characteristic-determined PRC cut-off of < 44 had optimal discriminatory power (area under curve 0.92) for identifying MDI < 70, with 85% sensitivity (95% CI 0.58-0.96), 87% specificity (95% CI 0.81-0.92), 98% negative predictive value (95% CI 0.95-1), and 37% positive predictive value (95% CI 0.22-0.54). The PARCA-R has good concurrent validity and diagnostic utility for identifying cognitive delay in very-preterm infants at 2 years of age. It is useful for outcome measurement, developmental screening, and facilitating parental involvement at folow-up.