SQUID-based simultaneous detection of NMR and biomagnetic signals at ultra-low magnetic fields
SQUID-based simultaneous detection of NMR and biomagnetic signals at ultra-low magnetic fields
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DOI：
10.1109/tasc.2005.849978
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发表时间：
2005-06-01
影响因子：
1.8
通讯作者：
Kraus, RH
中科院分区：
文献类型：
--
作者：
Espy, MA;Matlachov, AN;Kraus, RH
核磁共振（NMR）和磁共振成像（MRI）在超低磁场（ULF，类似于mu T的磁场）下比在高磁场下有几个优势。其中包括窄线宽度、新型成像方案（如T）的可能性、加权图像以及降低系统成本和复杂性。此外，超高频核磁共振/核磁共振与超导量子干涉装置（squid）兼容，可以同时测量生物磁信号，这是传统系统无法提供的能力。基于squid的超高频MRI已经被证明，同时在超高频测量MEG和NMR也已经被证明。在本文中，我们将展示核磁共振同时进行心脏磁图（MCG）和脑磁断层图（MMG）也是可能的。另一个引人注目的应用核磁共振/MRI在ULF是直接测量神经元信号的磁共振结果的可能性。在本文中，我们同时探索MMG/NMR和MCG/NMR对T-2（*）中核磁共振信号的影响，这可能与生物电电流的影响有关。
Nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI) at ultra-low magnetic fields (ULF, fields of similar to mu T) have several advantages over their counterparts at higher magnetic fields. These include narrow line widths, the possibility of novel imaging schemes such as T, weighted images, and reduced system cost and complexity. In addition, ULF NMR/MRI with superconducting quantum interference devices (SQUIDs) is compatible with simultaneous measurements of biomagnetic signals, a capability conventional systems cannot offer. SQUID-based ULF MRI has already been demonstrated, as have measurements of simultaneous MEG and NMR at ULF. In this paper we will show simultaneous magnetocardiography (MCG) and magnetomyography (MMG) with NMR are also possible. Another compelling application of NMR/MRI at ULF is the possibility of directly measuring magnetic resonance consequences of neuronal signals. In this paper we explore simultaneous MMG/NMR and MCG/NMR for an effect on the NMR signal, in T-2(*), that might be associated with the effects of bioelectric currents.