Knowledge and attitudes about male circumcision for HIV-1 prevention among heterosexual HIV-1 serodiscordant partnerships in Kampala, Uganda.
Knowledge and attitudes about male circumcision for HIV-1 prevention among heterosexual HIV-1 serodiscordant partnerships in Kampala, Uganda.
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DOI：
10.1007/s10461-010-9696-x
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发表时间：
2010-10
影响因子：
4.4
通讯作者：
Whalen C
中科院分区：
文献类型：
--
作者：
Mugwanya KK;Baeten JM;Nakku-Joloba E;Katabira E;Celum C;Tisch D;Whalen C
男性包皮环切术预防艾滋病毒-1将需要高风险人群的高度吸收。乌干达坎帕拉的318对HIV-1血清不一致夫妇[155对（48.7%）有HIV-1未感染男性伴侣]接受了关于男性包皮环切术预防HIV-1的访谈。77.1%的男性和89.6%的女性知道包皮环切术可以降低男性感染艾滋病毒的风险。几乎所有人都了解包皮环切术对HIV-1感染的部分保护作用，以及包皮环切术对HIV-1感染者的HIV-1传播的减少作用。在未行包皮环切术的HIV-1阴性男性（n = 92）夫妇中，53.3%的男性和88.1%的女性伴侣表示对男性包皮环切术感兴趣。这对夫妇之前关于包皮环切术预防HIV-1的讨论与对该手术的兴趣显著相关。在乌干达，HIV-1血清不一致的夫妇对男性包皮环切术对HIV-1预防的部分保护作用表现出高度的理解，但只有一半的HIV-1未感染的未包皮环切男性表示对该程序感兴趣。
Male circumcision for HIV-1 prevention will require high uptake among at-risk populations. 318 HIV-1 serodiscordant couples in Kampala, Uganda [155 (48.7%) with HIV-1 uninfected male partners] were interviewed about male circumcision for HIV-1 prevention. 77.1% of men and 89.6% of women were aware that circumcision reduces men’s risk for HIV-1 acquisition. Almost all understood the partial protective efficacy of circumcision for HIV-1 acquisition and lack of reduced HIV-1 transmission from circumcising HIV-1 infected men. Among couples with uncircumcised HIV-1 negative men (n = 92), 53.3% of men and 88.1% of female partners expressed interest in male circumcision. Previous discussion within the couple about circumcision for HIV-1 prevention was significantly associated with interest in the procedure. HIV-1 serodiscordant couples in Uganda demonstrated a high level of understanding of the partial protective effect of male circumcision for HIV-1 prevention, but only half of HIV-1 uninfected uncircumcised men expressed interest in the procedure.