Histone and histone gene compilation and alignment update.
Histone and histone gene compilation and alignment update.
复制标题
组蛋白和组蛋白基因编译和比对更新。
DOI：
10.1093/nar/19.suppl.2173
复制
发表时间：
1991
影响因子：
14.9
通讯作者：
Brown,D
中科院分区：
文献类型：
--
作者：
Wells,D;Brown,D
PROTEIN SEQUENCES Data from direct amino acid sequence analysis along with data from translated gene sequences are presented for each of the histone subtypes (Figures 1-5). Consensus sequences were generated for each histone subgroupbased on cumulative sequence information from this and the previouscompilation. Numbering is based on the consensus sequence. Figure 1 shows the alignments for the Hi proteins. In this figure the alignments ofHI and H5/H1. 0 variants are shown separately to emphasize the similarity of the vertebrate H5/H1. 0 group. The (@) symbols immediately above the H5 consensus indicate amino acids shared in the two variant groups. For the HI histones, only the central conserved hydrophobic region could be aligned with any degree of certainty. A dash (-) in a sequence indicates an unsequenced region. Blank spaces in the protein alignments indicate deletions with respect to the consensus. An asterisk (*) in the consensus indicates the absence ofa consensus amino acid for that position. A gap in the consensus sequence indicates an insertion was introduced into at least one of the aligned sequences to maximize sequence similarity. A dot (.) below a consensus amino acid indicates identity with that amino acid.
