Comment on 'Cytokeratin 20-negative Merkel cell carcinoma is infrequently associated with the Merkel cell polyomavirus'.

Comment on 'Cytokeratin 20-negative Merkel cell carcinoma is infrequently associated with the Merkel cell polyomavirus'.
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对“细胞角蛋白 20 阴性默克尔细胞癌很少与默克尔细胞多瘤病毒相关”的评论。

DOI:
10.1038/modpathol.2015.69
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发表时间:
2016
期刊:
Mod Pathol.
影响因子:
--
通讯作者:
Hayashi K.
Hayashi K.
中科院分区:
--
文献类型:
--
作者:
Iwasaki T;Matsushita M;Nonaka D;Murakami I;Hayashi K.

文献摘要

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3松下M,岩崎T,久本S等人。日本默克尔细胞癌(MCC)中的MCPyV株不同于高加索类型的MCPyV:从感染MCPyV的MCC中获得的MCPyV基因组的遗传变异和系统发育。病毒基因2014;48:233-242。4 Laude HC,Jonchere B,Maubec E等人。默克尔细胞癌患者肿瘤和非肿瘤标本中明显的默克尔细胞多瘤病毒分子特征。《公共科学图书馆》2010年版;6:e1001076。5 Kim JH,Rhee YY,Bae JM等人。在微卫星不稳定的结直肠癌中,CDX2/CK20表达缺失与低分化癌、CpG岛甲基化表型和不良预后相关。AM J Surg Pathol 2013;37:1532-1541。6岩崎T,松下M,久本S等人。显著的形态学特征在区分Merkel细胞多瘤病毒阳性和Merkel细胞多瘤病毒阴性的Merkel细胞癌中的作用。《Hum Pathol 2013》;44:1912-1917。
3 Matsushita M, Iwasaki T, Kuwamoto S et al. Merkel cell polyomavirus (MCPyV) strains in Japanese merkel cell carcinomas (MCC) are distinct from Caucasian type MCPyVs: genetic variability and phylogeny of MCPyV genomes obtained from Japanese MCPyV-infected MCCs. Virus Genes 2014; 48: 233–242. 4 Laude HC, Jonchere B, Maubec E et al. Distinct merkel cell polyomavirus molecular features in tumour and non tumour specimens from patients with merkel cell carcinoma. PLoS Pathog 2010; 6: e1001076. 5 Kim JH, Rhee YY, Bae JM et al. Loss of CDX2/CK20 expression is associated with poorly differentiated carcinoma, the CpG island methylator phenotype, and adverse prognosis in microsatellite-unstable colorectal cancer. Am J Surg Pathol 2013; 37: 1532–1541. 6 Iwasaki T, Matsushita M, Kuwamoto S et al. Usefulness of significant morphologic characteristics in distinguishing between Merkel cell polyomavirus-positive and Merkel cell polyomavirus-negative Merkel cell carcinomas. Hum Pathol 2013; 44: 1912–1917.