ANALYSIS OF SOME MALAYSIAN DART POISONS

ANALYSIS OF SOME MALAYSIAN DART POISONS
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DOI:
10.1016/0378-8741(92)90061-u
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发表时间:
1992-02-01
影响因子:
5.4
通讯作者:
BERNKOPSCHNURCH, A
BERNKOPSCHNURCH, A
中科院分区:
医学2区
文献类型:
--
作者:
KOPP, B;BAUER, WP;BERNKOPSCHNURCH, A

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对九种马来西亚箭毒的研究证实,其主要活性成分是来自见血封喉(Antiaris toxicaria (Pers.) Lesch.)的强心苷以及可能来自不同种类吕宋豆(Strychnos ignatii P. Bergius)的生物碱。仅根据分析结果无法确定这些毒药的民族来源。已分离出两种新的强心苷,其结构分别确定为12 -β -羟基康纳苷元3 -β -O -β -D -脱氧古洛吡喃糖苷和3 -β -O -α -L -鼠李吡喃糖苷。
An investigation of nine Malaysian dart poisons has confirmed that their main active components are cardenolides from Antiaris toxicaria (Pers.) Lesch. and alkaloids probably from different forms of Strychnos ignatii P. Bergius. It is not possible to determine the ethnic origin of the poisons from the results of the analyses on their own. Two new cardiac glycosides have been isolated and their structures determined as 12-beta-hydroxycannogenin 3-beta-O-beta-D-deoxygulopyranoside and 3-beta-O-alpha-L-rhamnopyranoside, respectively.