Specific Peptide Regulated Synthesis of Ultrasmall Platinum Nanocrystals
Specific Peptide Regulated Synthesis of Ultrasmall Platinum Nanocrystals
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DOI：
10.1021/ja907235v
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发表时间：
2009-11-11
影响因子：
15
通讯作者：
Huang, Yu
中科院分区：
文献类型：
--
作者：
Li, Yujing;Whyburn, Gordon P.;Huang, Yu
我们展示了单分散超小铂(铂)纳米晶体(NCS)的合理合成，在室温的水溶液中，通过特定选择的多肽分子。利用噬菌体展示技术筛选出的铂结合肽可以作为稳定剂来调节铂晶体的成核和生长，从而控制最终的铂纳米管的形态和尺寸。得到了尺寸在1.73~3.54 nm之间的均匀的近球形的铂纳米管，其尺寸分布非常窄。多肽稳定的铂纳米管在水中可以很好地分散数月。还证明了多肽与铂纳米管表面的强结合是可逆的，无论是通过调节pH还是多肽光解。
We demonstrate the rational synthesis of monodisperse ultrasmall platinum (Pt) nanocrsytals (NCs), in aqueous solution at room temperature, with specifically selected peptide molecules. The specific Pt-binding peptide, selected using a phage display technique, can function as a stabilizer to regulate Pt crystal nucleation and growth and, therefore, control both the morphology and size of the final Pt NCs. Uniform near-spherical Pt NCs with sizes ranging from 1.73 to 3.54 nm were achieved with a very narrow size distribution. The peptide-stabilized Pt NCs can be dispersed well in water for months. It was also demonstrated that the strong binding of peptides to the Pt NC surface is reversible by either pH modulation or peptide photolysis.