Application of a calibration method provides more realistic results for a finite element model of a lumbar spinal segment
Application of a calibration method provides more realistic results for a finite element model of a lumbar spinal segment
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DOI：
10.1016/j.clinbiomech.2006.11.008
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发表时间：
2007-05-01
影响因子：
1.8
通讯作者：
Wilke, Hans-Joachim
中科院分区：
文献类型：
--
作者：
Schmidt, Hendrik;Heuer, Frank;Wilke, Hans-Joachim
背景有限元建模的一个重要步骤是验证以获得临床相关数据的过程。可以假设，以前未被验证的有限元模型的缺陷状态可能预测错误的结果。本研究的目的是显示校准和未校准的腰椎节段有限元模型对不同临床缺陷的准确性差异。在这项研究中，使用了两个几何相同的有限元模型。设计了一项体外实验，为校准提供数据。常用的材料特性从文献中获得，并转移到未校准的模型中。这两个模型都在三种临床缺陷上得到了验证：双侧小关节切除、髓核摘除和棘间缺陷，而体外运动范围的数据作为控制点。对校准后和未校准后的有限元模型的可预测性和准确性进行了评估和比较。两种有限元模型都能很好地模拟完整的情况。在缺陷中，校准后的模型对运动行为的预测具有很好的一致性，而未校准的模型则有很大的差异。通过数值分析来研究种植体的生物力学性能和不同脊柱结构的载荷分布，不仅需要与完整的节段吻合，而且需要与种植体植入前开始的缺陷状态保持良好的一致性。由于结果更接近实际，可能会推荐使用校准方法，但这种方法耗时较长。(C)2006爱思唯尔有限公司。保留所有权利。
Background An important step in finite element modeling is the process of validation to derive clinical relevant data. It can be assumed that defect states of a finite element model, which have not been validated before, may predict wrong results. The purpose of this study was to show the differences in accuracy between a calibrated and a non-calibrated finite element model of a lumbar spinal segment for different clinical defects.Methods. For this study, two geometrically identical finite element models were used. An in vitro experiment was designed, deriving data for the calibration. Frequently used material properties were obtained from the literature and transferred into the non-calibrated model. Both models were validated on three clinical defects: bilateral hemifacetectomy, nucleotomy and interspinous defects, whereas in vitro range of motion data served as control points. Predictability and accuracy of the calibrated and non-calibrated finite element model were evaluated and compared.Findings. Both finite element models could mimic the intact situation with a good agreement. In the defects, the calibrated model predicted motion behavior with excellent agreement, whereas the non-calibrated model diverged greatly.Interpretation. Investigating the biomechanical performance of implants and load distribution of different spinal structures by numerical analysis requires not only good agreement with the intact segment, but also with the defect states, which are initiated prior to implant insertion. Because of more realistic results the calibration method may be recommended, however, it is more time consuming. (c) 2006 Elsevier Ltd. All rights reserved.