Rhesus monkey and human share a similar topography of the corpus callosum as revealed by diffusion tensor MRI in vivo
Rhesus monkey and human share a similar topography of the corpus callosum as revealed by diffusion tensor MRI in vivo
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DOI：
10.1093/cercor/bhm141
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发表时间：
2008-05-01
期刊：
影响因子：
3.7
通讯作者：
Frahm, Jens
中科院分区：
文献类型：
--
作者：
Hofer, Sabine;Merboldt, Klaus-Dietmar;Frahm, Jens
最近一项对人类胼胝体(CC)的研究揭示了皮质连接模式的一种新的地形图排列。为了探索非人类灵长类动物的CC地形图，我们应用了磁共振扩散张量成像和活体内单个恒河猴的轨迹追踪技术。结果表明，灵长类动物和人类的CC地形图惊人地相似。具体地说，在猴和人脑中都观察到了CC中较大的连合额纤维的表达和尾部延伸。如果相对脑体积的进化变化反映在穿过CC的相关纤维的排列上，那么目前的研究符合这样一个事实，即在人系从其他灵长类动物中分离出来后，额叶的相对体积并没有显著增加。
A recent study of the corpus callosum (CC) in humans revealed a new topographical arrangement of the cortical connectivity pattern. To explore the CC topography in nonhuman primates, we applied magnetic resonance diffusion tensor imaging and tract tracing techniques in individual rhesus monkeys in vivo. The results demonstrate that the CC topography of primates and humans is surprisingly similar. In particular, the relatively large representation and caudal extension of commissural frontal fibers in the CC is observed in both the monkey and human brain. If evolutionary changes in relative brain volumes are reflected in the arrangement of related fibers crossing the CC, the current study is in line with the fact that the relative volume of the frontal lobe did not significantly increase after the split of the hominid line from other primates.