Alterations of left ventricular myocardial characteristics associated with obesity
Alterations of left ventricular myocardial characteristics associated with obesity
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DOI：
10.1161/01.cir.0000147184.13872.0f
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发表时间：
2004-11-09
期刊：
影响因子：
37.8
通讯作者：
Marwick, TH
中科院分区：
文献类型：
--
作者：
Wong, CY;O'Moore-Sullivan, T;Marwick, TH
背景：肥胖与心力衰竭有关，但体重对心脏结构和功能的影响（独立于合并症）尚未得到很好的证实。我们寻求身体质量指数（BMI）和胰岛素水平是否与亚临床心肌紊乱相关。方法与结果：109例超重或肥胖患者、33例参考患者（BMI35）和参考患者（P . 35）的经胸超声心动图、心肌多普勒收缩（sm）和早期舒张速度（em）、应变和应变率成像、循环变异组织特征（CVIB）和校准后向散射（cIB）
Background-Obesity is associated with heart failure, but an effect of weight, independent of comorbidities, on cardiac structure and function is not well established. We sought whether body mass index (BMI) and insulin levels were associated with subclinical myocardial disturbances.Methods and Results-Transthoracic echocardiography, myocardial Doppler-derived systolic (sm) and early diastolic velocity ( em), strain and strain rate imaging and tissue characterization with cyclic variation (CVIB), and calibrated integrated backscatter (cIB) were obtained in 109 overweight or obese subjects and 33 referents (BMI35) and the referent patients (P