Effect of nicotine on negative affect among more impulsive smokers
Effect of nicotine on negative affect among more impulsive smokers
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DOI：
10.1037/1064-1297.14.3.287
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发表时间：
2006-08-01
影响因子：
2.3
通讯作者：
Cook, Jessica Werth
中科院分区：
文献类型：
--
作者：
Doran, Neal;VanderVeen, Joe;Cook, Jessica Werth
在目前的研究中，作者测试了这样一个假设，即尼古丁对更冲动的吸烟者比对不那么冲动的吸烟者提供更大的负面情绪缓解。心境愉悦的成年吸烟者(N=70)参加了两个实验室会议，在此期间，他们接受了负面情绪诱导(音乐+自传体记忆)，然后吸食尼古丁或非尼古丁香烟。混合效应回归得到显著的冲动性X条件(烟碱化与去烟碱化)X时间交互作用。简单的效应分析表明，高冲动性预示着吸了尼古丁香烟后负面情绪会得到更大的缓解，而不是吸了去尼古丁香烟之后。这些数据表明，对于高度冲动的吸烟者来说，尼古丁可能是一种不成比例的强大负面增强剂，促进了更高水平的尼古丁依赖，并抑制了戒烟。
In the present study, the authors tested the hypothesis that nicotine would provide greater relief from negative affect for more impulsive smokers than for less impulsive smokers. Euthymic adult smokers (N = 70) participated in 2 laboratory sessions, during which they underwent a negative mood induction (music + autobiographical memory), then smoked either a nicotinized or de-nicotinized cigarette. Mixed-effects regression yielded a significant Impulsivity X Condition (nicotinized vs. de-nicotinized) X Time interaction. Simple effects analyses showed that heightened impulsivity predicted greater negative affect relief after smoking a nicotinized cigarette but not after smoking a de-nicotinized cigarette. These data suggest that nicotine may be a disproportionately powerful negative reinforcer for highly impulsive smokers, promoting higher levels of nicotine dependence and inhibiting smoking cessation.