Postprandial reduction in blood pressure in the elderly.
Postprandial reduction in blood pressure in the elderly.
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老年人餐后血压降低。
DOI：
10.1056/nejm198307143090205
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发表时间：
1983
期刊：
影响因子：
--
通讯作者：
Rowe,JW
中科院分区：
文献类型：
--
作者：
Lipsitz,LA;NyquistJr,RP;Wei,JY;Rowe,JW
我们评估了膳食对老年机构受试者收缩压和心率的影响（平均年龄±S.E.M.，（87±1）例有或无晕厥史者和年轻正常人。在试验餐前和试验餐后60分钟内测量脉搏和血压。到35分钟时，10名有晕厥的老年受试者的平均收缩压最大下降了25±5 mm Hg，10名无晕厥的老年受试者的平均收缩压最大下降了24±9 mm Hg（P<0.03），然后该水平稳定下来，直到60分钟没有进一步变化。11名未进食的年轻受试者和老年受试者的血压没有变化，餐后收缩压的变化与药物或诊断无关。老年人的代偿性心脏加速最小，表明压力反射受损。我们的观察表明，餐后血压降低可能使老年人易患症状性低血压。（N Engl J Med 1983; 309：81-3.）
We evaluated the effects of a meal on systolic blood pressure and heart rate in elderly institutionalized subjects (mean age ±S.E.M., 87±1) with and without histories of syncope and in young normal subjects. Pulse and blood pressure were measured before the test meal and at intervals for up to 60 minutes afterward. By 35 minutes mean systolic blood pressure had declined a maximum of 25±5 mm Hg in 10 elderly subjects with syncope and 24±9 mm Hg in 10 elderly subjects without syncope (P<0.03); the level then stabilized without further change until 60 minutes. There were no changes in blood pressure in 11 young subjects or in elderly subjects not given a meal.The postprandial change in systolic pressure was not related to medications or diagnoses. Compensatory cardioacceleration was minimal in the elderly, suggesting impaired baroreflexes. Our observations show that postprandial reductions in blood pressure may predispose the elderly to symptomatic hypotension. (N Engl J Med 1983; 309:81–3.)