CHANGES IN COMPARTMENTAL VENTILATION IN ASSOCIATION WITH EYE-MOVEMENTS DURING REM-SLEEP
CHANGES IN COMPARTMENTAL VENTILATION IN ASSOCIATION WITH EYE-MOVEMENTS DURING REM-SLEEP
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DOI：
10.1152/jappl.1988.65.3.1196
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发表时间：
1988-09-01
影响因子：
3.3
通讯作者：
PACK, AI
中科院分区：
文献类型：
--
作者：
MILLMAN, RP;KNIGHT, H;PACK, AI
通过使用呼吸感应体积描记器，研究了七名健康年轻人在快速眼动 (REM) 睡眠期间阶段性眼动活动对通气的影响。快速眼动睡眠期间的平均通气量 (.ovrhdot.VE) 和通气成分与 1-2 或 3-4 阶段睡眠中的情况没有显着差异。快速眼动睡眠期间胸腔对通气的贡献百分比，29.3 .+-。 5.1%，较54.5±减少。第 1-2 阶段为 5.8%，52.2 .+-。 4.3% 处于第 3-4 阶段睡眠（P < 0.005）。当一个人根据相关的阶段性眼动活动的程度来分开呼吸时，很明显，快速眼动睡眠期间的呼吸是非常不均匀的。眼动活动的增加与通气的抑制相关，其中.ovrhdot.VE从5.1.+-减少。 0.3 至 3.8.+-。 0.3 升/分钟。潮气量和频率均下降，而吸气持续时间没有变化。隔室通气也受到影响，胸腔贡献从 37.8 .+- 下降。 6.4.+-. 15.3.+-. 5.6%。随着阶段性眼动活动的增加，胸壁和腹部的运动变得更加不同步，并且出现明显的矛盾呼吸。
The effect of phasic eye movement activity on ventilation during rapid-eye-movement (REM) sleep was studied in seven healthy young adults by use of the respiratory inductive plethysmograph. Mean ventilation (.ovrhdot.VE) and ventilatory components during REM sleep were not significantly different from that seen in either stages 1-2 or 3-4 sleep. The percent of rib cage contribution to ventilation in REM sleep, 29.3 .+-. 5.1%, was reduced compared with 54.5 .+-. 5.8% in stage 1-2 and 52.2 .+-. 4.3% in stage 3-4 sleep (P < 0.005). When one separated breaths by the degree of associated phasic eye movement activity, it became apparent that breathing during REM sleep is very heterogeneous. Increasing eye movement activity was associated with inhibition of ventilation with a reduction in .ovrhdot.VE from 5.1 .+-. 0.3 to 3.8 .+-. 0.3 l/min. Tidal volume and frequency both fell, whereas inspiratory duration was unchanged. Compartmental ventilation was also affected, with the fall in the rib cage contribution from 37.8 .+-. 6.4 .+-. 15.3 .+-. 5.6%. Chest wall and abdominal movement became more asynchronous as phasic-eye-movement activity increased and frank paradoxical breathing was seen.