Effects of alcohol and cigarette consumption on human seminal quality
Effects of alcohol and cigarette consumption on human seminal quality
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DOI：
10.1016/j.fertnstert.2004.03.022
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发表时间：
2004-08-01
影响因子：
6.7
通讯作者：
Ruiz, RD
中科院分区：
文献类型：
--
作者：
Martini, AC;Molina, RI;Ruiz, RD
目的：评估饮酒或吸烟对男性实验室男性精液参数的影响。设计：十年数据分析（1990-1999年），单位：男科学和生殖实验室患者：患者（3，976）根据不吸烟者分组;小于或等于20支/天; >20支/天;非酒精消费者;少于或等于500 mL葡萄酒（类似于52 g乙醇）或同等物/天;以及>500 mL葡萄酒或同等物/天。饮酒和吸烟的患者也被考虑。干预措施：由患者自愿填写问卷。它提供了药物消耗和泌尿生殖系统疾病的数据。主要结果测量：精液量，精子浓度，活力，活力和形态。结果：酒精或烟草消耗程度之间的精液参数无统计学差异;因此，独立于消耗程度，患者被认为是吸烟者或酒精消费者。饮酒或吸烟不会改变精液参数。然而，当有这两种习惯的患者与没有这些习惯的患者相比时，检测到精液量、精子浓度、活动精子百分比显著减少，而非活动活配子显著增加。这两个有毒的习惯的协同或相加作用进行了讨论。（Fertil Steril（（R））2004;82：374-7. (C)2004年，美国生殖医学会（American Society for Reproductive Medicine）。
Objective: To evaluate the effects of alcohol or cigarette consumption on seminal parameters in a large population of men attending an andrology laboratory.Design: Analysis of ten years of data (1990-1999).Setting: Andrology and Reproduction Laboratory (Cordoba, Argentina).Patient(s): Patients (3,976) were grouped according to nonsmokers; less than or equal to20 cigarettes/day; >20 cigarettes/day; nonalcohol consumers; less than or equal to500 mL of wine (similar to52 g of ethanol) or equivalent/day; and >500 mL of wine or equivalent/day. Patients who drank alcohol and smoked were also considered.Intervention(s): A questionnaire was voluntarily filled out by patients. It provided data on drug consumption and genitourinary diseases.Main Outcome Measure(s): Seminal volume, sperm concentration, motility, viability, and morphology.Results: No statistical differences in seminal parameters were found between the degrees of alcohol or tobacco consumption; so, independently of the degree of consumption patients were considered as smokers or alcohol consumers.Conclusion(s): Alcohol or cigarette consumption did not alter the seminal parameters. Nevertheless, when the patients with these two habits were compared to those without these habits, a significant reduction in seminal volume, sperm concentration, percentage of motile spermatozoa, and a significant increase of the nonmotile viable gametes were detected. The synergic or additive effect of these two toxic habits is discussed. (Fertil Steril((R)) 2004;82:374-7. (C) 2004 by American Society for Reproductive Medicine.).