Cortisol Awakening Response and Heart Rate Variability in the Menstrual Cycle of Sportswomen
Cortisol Awakening Response and Heart Rate Variability in the Menstrual Cycle of Sportswomen
复制标题
DOI：
10.1080/02701367.2020.1774486
复制
发表时间：
2020-08-29
影响因子：
2.2
通讯作者：
Yildiz, Sedat
中科院分区：
文献类型：
--
作者：
Kayacan, Yildirim;Makaraci, Yucel;Yildiz, Sedat
目的：检测女性运动员月经周期中自主神经系统(ANS)和下丘脑-垂体-肾上腺轴(HPA)的心率变异性(HRV)和皮质醇分泌活动。方法：对28名受试者在月经周期4个时相(月经期、排卵期、黄体期和经前期)分别于睡醒后0、15、30、60min采集唾液样本，测定皮质醇唤醒反应(CAR)。分别在中午、晚上(17：00)和22：00采集唾液样本进行皮质醇分析。结果：月经期CAR参数与经期CAR参数无明显差异，CAR参数与每日皮质醇水平在整个月经周期内呈显著正相关。平均皮质醇是曲线下面积的有力预测因子(AUC：S=0.042；R-Sq=98.4%)。心率变异性的时间相关参数(N-N间期的标准差[SDNN；P=.049]和连续R-R差值的均方根[rMSSD；P=.038])在月经期显著升高。CAR与HRV参数之间无相关性。结论：我们认为女性运动员下丘脑-垂体-肾上腺轴的活动和自主神经系统以独立的方式工作，不受月经时相的影响。本研究有助于更好地了解女运动员月经周期不同阶段皮质醇释放动力学与自主神经系统的关系。
Purpose: This study aimed to examine the activities of heart rate variability (HRV) and cortisol secretion as markers of the autonomous nervous system (ANS) and the hypothalamic-pituitary-adrenal axis (HPA) during the menstrual cycle in female athletes.Method: Saliva samples of the participants (n = 28) were collected successively at 0, 15, 30, and 60 min after awakening to assess cortisol awakening response (CAR) during each of four phases of the menstrual cycle (the menstruation, ovulation, luteal, and premenstrual phases). Diurnal saliva samples were collected at noon, in the evening (17:00) and 22:00 for cortisol analysis. HRV was measured in the menstrual and premenstrual phases at rest (12:00-14:00).Results: There was no difference betweenCARparameters in the menstrual phases.CARparameters and diurnal cortisol levels were significantly correlated with each other throughout the menstrual cycle. Mean cortisol was a strong predictor of the area under the curve (AUC: S = 0.042; R-Sq = 98.4%). Time-dependent parameters of HRV (standard deviation of the N-N interval [SDNN;P= .049] and the root mean square of the successive R-R differences [rMSSD;P= .038]) were significantly higher in the menstrual phase. There were no correlations betweenCARand HRV parameters.Conclusions: We suggest that the hypothalamic-pituitary-adrenal axis activity and the autonomic nervous system work in a separate manner that is not affected by the menstrual phases in sportswomen. The present study contributed to a better understanding of the relationship between the dynamics of cortisol release and the autonomic nervous system in different phases of the menstrual cycle in female athletes.