Selective dopamine transporter inhibition by cocaine analogs.
Selective dopamine transporter inhibition by cocaine analogs.
复制标题
可卡因类似物选择性多巴胺转运蛋白抑制。
DOI：
10.1097/00001756-199211000-00009
复制
发表时间：
1992
期刊：
影响因子：
1.7
通讯作者：
Kuhar,MJ
中科院分区：
文献类型：
--
作者：
Boja,JW;McNeill,RM;Lewin,AH;Abraham,P;Carroll,FI;Kuhar,MJ
可卡因的3 [β]-（4-取代苯基）托品烷-2 [β]-羧酸类似物的几种异丙基酯和苯基酯在抑制多巴胺摄取方面比可卡因和一些其它化合物相对更有效和更有选择性。这些类似物可用作结合配体和作为阐明可卡因作用机制的工具。
SEVERAL isopropyl and phenyl esters of 3 [beta]-(4-substituted phenyl) tropan-2 [beta]-carboxylic acid analogs of cocaine are relatively more potent and selective than cocaine and some other compounds in inhibiting dopamine uptake. These analogs can be used as binding ligands and as tools for elucidating the mechanisms of action of cocaine.