[Myocardial remodeling].

[Myocardial remodeling].
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DOI：
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发表时间：
2003
期刊：
Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi
影响因子：
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通讯作者：
R. Artenie;A. Artenie;D. Ungureanu;I. Haulica;A. Coşovanu
R. Artenie;A. Artenie;D. Ungureanu;I. Haulica;A. Coşovanu
中科院分区：
其他
文献类型：
--
作者：
R. Artenie;A. Artenie;D. Ungureanu;I. Haulica;A. Coşovanu

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心室重塑和心肌收缩功能障碍在心肌梗死后心力衰竭的发生发展中发挥重要作用。该过程伴随着调节细胞生长和收缩功能的基因表达和再表达的质和量的变化。本文试图从临床角度并同时从分子角度解释心肌重塑的一些机制，这些机制允许心脏对正常和病理条件进行修改和适应。
Chamber remodeling and myocardial systolic dysfunction play an important role in the development of cardiac failure after myocardial infarction. The process is accompanied by qualitative and quantitative changes in the expression and reexpression of genes regulating cell growth and contractile function. The article tries to explain some of the mechanisms of the myocardial remodeling that permit the modifications and adaptation of the heart to normal and pathological conditions from a clinical point of view and, in the same time, from a molecular point of view.