Assessing the Discriminant Ability, Reliability, and Comparability of Multiple Short Forms of the Boston Naming Test in an Alzheimer's Disease Center Cohort

Assessing the Discriminant Ability, Reliability, and Comparability of Multiple Short Forms of the Boston Naming Test in an Alzheimer's Disease Center Cohort
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DOI:
10.1159/000370108
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发表时间:
2015-01-01
影响因子:
2.4
通讯作者:
Fardo, David W.
Fardo, David W.
中科院分区:
医学4区
文献类型:
--
作者:
Katsumata, Yuriko;Mathews, Melissa;Fardo, David W.

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背景资料:波士顿命名测验(BNT)是一种常用的对抗命名神经心理学测试,有助于确定命名障碍的存在和严重程度。最初的60项测试的许多简短版本已经开发出来,并在临床/研究环境中进行常规管理。由于共同需要翻译类似的措施内和跨研究,重要的是要评估不同的BNT版本的操作特性和协议。研究方法:我们分析了来自肯塔基州大学阿尔茨海默病中心纵向队列的研究志愿者(n = 681)的纵向数据。结论:除了建立阿尔茨海默病登记处联盟(CERAD)15项BNT的显著例外,简短的形式内部一致,与完整版本高度相关;这些措施因诊断而异,通常从正常改善到轻度认知障碍(MCI)到痴呆。所有简短的表格都保留了区分正常受试者和痴呆症受试者的能力。区别正常和MCI受试者的能力是不太强的短形式比完整的BNT,但他们表现出类似的模式。这些结果对设计纵向研究的研究人员具有重要意义,他们必须考虑到即使是密切相关的测试形式的统计特性也可能是完全不同的。(C)2015 S. Karger AG,巴塞尔
Background: The Boston Naming Test (BNT) is a commonly used neuropsychological test of confrontation naming that aids in determining the presence and severity of dysnomia. Many short versions of the original 60-item test have been developed and are routinely administered in clinical/research settings. Because of the common need to translate similar measures within and across studies, it is important to evaluate the operating characteristics and agreement of different BNT versions. Methods: We analyzed longitudinal data of research volunteers (n = 681) from the University of Kentucky Alzheimer's Disease Center longitudinal cohort. Conclusions: With the notable exception of the Consortium to Establish a Registry for Alzheimer's Disease (CERAD) 15-item BNT, short forms were internally consistent and highly correlated with the full version; these measures varied by diagnosis and generally improved from normal to mild cognitive impairment (MCI) to dementia. All short forms retained the ability to discriminate between normal subjects and those with dementia. The ability to discriminate between normal and MCI subjects was less strong for the short forms than the full BNT, but they exhibited similar patterns. These results have important implications for researchers designing longitudinal studies, who must consider that the statistical properties of even closely related test forms may be quite different. (C) 2015 S. Karger AG, Basel