Falls Are Associated with Stroke, Arthritis and Multiple Medications among Community-Dwelling Elderly Persons in Japan
Falls Are Associated with Stroke, Arthritis and Multiple Medications among Community-Dwelling Elderly Persons in Japan
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DOI：
10.1620/tjem.231.299
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发表时间：
2013-12-01
影响因子：
2.2
通讯作者：
Aoyagi, Kiyoshi
中科院分区：
文献类型：
--
作者：
Mizukami, Satoshi;Arima, Kazuhiko;Aoyagi, Kiyoshi
福尔斯是一个重大的公共卫生问题，也是仅次于道路交通事故的第二大意外伤害致死原因。患有多种慢性疾病的不活跃的老年人比活跃和健康的老年人更容易跌倒。在日本，尚无基于人群的研究同时探讨中风、关节炎、催眠药和其他处方药与老年人福尔斯跌倒的相关性。我们研究了日本社区居住老年人中福尔斯的患病率，这些老年人是从居民登记处编制的年龄≥ 65岁的居民名单中随机选择的，我们还研究了福尔斯与中风、关节炎、催眠药和其他处方药之间的关系。我们访问了295名男性和307名女性，并收集了最近一年内福尔斯的数量、中风偏瘫、腿部关节炎以及催眠药和其他药物的数量等信息。我们发现，46名男性（16%）和67名女性（22%）在最近一年内至少摔倒过一次。校正年龄后的Logistic回归分析显示，中风所致偏瘫（p < 0.001）、腿部关节炎（p < 0.001）和每日至少服用四种处方药（p < 0.05）与男性福尔斯显著相关。腿部关节炎（p = 0.05）和每天至少服用四种处方药（p < 0.05）与女性福尔斯跌倒有关。跌倒相关疾病的治疗和药物管理是减少老年人跌倒福尔斯的重要策略。
Falls are a major public health problem and the second leading cause of death due to unintentional accidental injury after road traffic accidents. Inactive, older individuals with several chronic illnesses fall more frequently than older individuals who are active and healthy. No population-based study has addressed the association of stroke, arthritis, hypnotic and other prescription medications with falls among the elderly simultaneously in a single population in Japan. We examined the prevalence of falls among community-dwelling elderly Japanese individuals, whom we randomly selected from a list of inhabitants aged >= 65 years compiled from the resident registration, and the associations between falls and each of stroke, arthritis, and hypnotic and other prescription medications. We interviewed 295 men and 307 women, and collected information about the number of falls during the latest one year, hemiplegia due to stroke, arthritis in the legs, and the number of hypnotic and other medications. We found that 46 men (16%) and 67 women (22%) had fallen at least once during the latest one year. Logistic regression analysis adjusted for age showed that hemiplegia due to stroke (p < 0.001), arthritis in the legs (p < 0.001), and taking at least four daily prescription medications (p < 0.05) were significantly associated with falls in men. Arthritis in the legs (p = 0.05) and taking at least four daily prescription medications (p < 0.05) were associated with falls in women. Treatment of fall-related diseases and medication management are important strategies for reducing falls among elderly persons.