Animal-to-animal variability in motor pattern production in adults and during growth
Animal-to-animal variability in motor pattern production in adults and during growth
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DOI：
10.1523/jneurosci.3679-04.2005
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发表时间：
2005-02-16
影响因子：
5.3
通讯作者：
Marder, E
中科院分区：
文献类型：
--
作者：
Bucher, D;Prinz, AA;Marder, E
在神经系统的生长过程中，以及在相同大小的不同准备过程中，网络输出的哪些特征得到了很好的保留？为了解决这个问题，我们的特征胃神经系统的99个成人和12个少年龙虾（美洲龙虾）的幽门节律。单个幽门神经元和整个口胃神经节（STG）的解剖学研究表明，STG及其神经元从幼年到成年有相当大的增长。尽管这些变化的大小，胞内记录的膜电位波形的幽门网络神经元和幽门节律的相位关系是非常相似的青少年和成人的准备。在成人制剂中，周期周期和每次爆发的峰值数量没有严格保持，但平均相位关系与节律周期无关，并且在制剂中保持相对紧密。我们将其解释为网络活动的稳态调节的证据。
Which features of network output are well preserved during growth of the nervous system and across different preparations of the same size? To address this issue, we characterized the pyloric rhythms generated by the stomatogastric nervous systems of 99 adult and 12 juvenile lobsters (Homarus americanus). Anatomical studies of single pyloric network neurons and of the whole stomatogastric ganglion (STG) showed that the STG and its neurons grow considerably from juvenile to adult. Despite these changes in size, intracellularly recorded membrane potential waveforms of pyloric network neurons and the phase relationships in the pyloric rhythm were very similar between juvenile and adult preparations. Across adult preparations, the cycle period and number of spikes per burst were not tightly maintained, but the mean phase relationships were independent of the period of the rhythm and relatively tightly maintained across preparations. We interpret this as evidence for homeostatic regulation of network activity.