Reduced heart rate variability and vagal tone in anxiety: Trait versus state, and the effects of autogenic training
Reduced heart rate variability and vagal tone in anxiety: Trait versus state, and the effects of autogenic training
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DOI：
10.1016/j.autneu.2008.11.010
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发表时间：
2009-01-28
影响因子：
2.7
通讯作者：
Miclea, Mircea
中科院分区：
文献类型：
--
作者：
Miu, Andrei C.;Heilman, Renata M.;Miclea, Mircea
本研究调查了健康志愿者的心率变异性（HRV），这些志愿者被选为特质焦虑（TA）的极端分数。在两种相反的心理生理条件下的心理应激和放松诱导的自生训练。R-R间期、HF和LF功率以及LF/HF比值来自于通过自生训练在精神应激和放松期间进行的短期心电图记录，在所有分析中控制呼吸频率和皮肤电导。主要发现是高TA与各种条件下R-R间期和HF功率的减少相关。与精神应激相比，自体训练增加了心率变异性，促进了心脏的迷走神经控制。TA或心理生理条件对LF功率或LF/HF比值无显著影响。这些结果支持了这样的观点，即TA，这是一个重要的危险因素焦虑症和心血管疾病的发病率和死亡率的预测因子，是与植物神经功能障碍，似乎可能在长期发挥致病作用。(c)2008 Elsevier B. V.保留所有权利。
This study investigated heart rate variability (HRV) in healthy volunteers that were selected for extreme scores of trait anxiety (TA). during two opposite psychophysiological conditions of mental stress, and relaxation induced by autogenic training. R-R intervals, HF and LF powers, and LF/HF ratios were derived from short-term electrocardiographic recordings made during mental stress and relaxation by autogenic training, with respiratory rate and skin conductance being controlled for in all the analyses. The main finding was that high TA was associated with reduced R-R intervals and HF power across conditions. In comparison to mental stress, autogenic training increased HRV and facilitated the vagal control of the heart. There were no significant effects of TA or the psychophysiological conditions on LF power, or LF/HF ratio. These results support the view that TA, which is an important risk factor for anxiety disorders and predictor of cardiovascular morbidity and mortality, is associated with autonomic dysfunction that seems likely to play a pathogenetic role in the long term. (c) 2008 Elsevier B.V. All rights reserved.