West Nile fever outbreak, Israel, 2000: Epidemiologic aspects
West Nile fever outbreak, Israel, 2000: Epidemiologic aspects
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DOI：
10.3201/eid0704.010416
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发表时间：
2001-07-01
影响因子：
11.8
通讯作者：
Chowers, MY
中科院分区：
文献类型：
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作者：
Weinberger, M;Pitlik, SD;Chowers, MY
从2000年8月1日至10月31日，以色列全国有417例经血清学证实的西尼罗河热病例，其中326例（78%）为住院患者。病例分布在全国各地;发病率最高的是以色列中部，人口最多的地区。男性和女性同样受到影响，他们的平均年龄为54 ± 23.8岁（范围6个月至95岁）。每千人的发病率从出生后10年的0.01增加到9年的0.87。有35例死亡（病死率8.4%），均为50岁以上的患者。随着年龄的增长，糖尿病特异性病死率也在增加。233例住院患者中有170例（73%）发生中枢神经系统受累。全国范围内的传播，住院人数，疾病的严重程度和高死亡率与以前报告的以色列爆发形成鲜明对比。
From August 1 to October 31, 2000, 417 cases of West Nile (WN) fever were serologically confirmed throughout Israel; 326 (78%) were hospitalized patients. Cases were distributed throughout the country; the highest incidence was in central Israel, the most populated part. Men and women were equally affected, and their mean age was 54 +/- 23.8 years (range 6 months to 95 years). Incidence per 1,000 population increased from 0.01 in the 1 st decade of life to 0.87 in the 9th decade. There were 35 deaths (case-fatality rate 8.4%), all in patients > 50 years of age. Age-specific case-fatality rate increased with age. Central nervous system involvement occurred in 170 (73%) of 233 hospitalized patients. The countrywide spread, number of hospitalizations, severity of the disease, and high death rate contrast with previously reported outbreaks in Israel.