Ethical considerations in international research collaboration: The Bucharest Early Intervention Project
Ethical considerations in international research collaboration: The Bucharest Early Intervention Project
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DOI：
10.1002/imhj.20107
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发表时间：
2006-11-01
影响因子：
2.4
通讯作者：
Nelson, Charles A.
中科院分区：
文献类型：
--
作者：
Zeanah, Charles H.;Koga, Sebastian F.;Nelson, Charles A.
布加勒斯特早期干预项目（BEIP）是有史以来第一个将寄养作为幼儿机构护理替代方案的随机对照试验。它涉及美国调查人员和罗马尼亚卫生和儿童保护专业人员之间的合作。在讨论该项目提出的一些伦理问题之前，我们简要介绍了罗马尼亚的背景和项目本身。围绕剥削，风险/收益比和文化敏感性的讨论，我们使用伦理临床研究框架和公平利益框架评估了BEIP中涉及的一些伦理问题。基于这一审查，我们得出结论，尽管具有挑战性的道德困境，该项目的好处超过了它的风险。在整个项目的规划和实施过程中，道德问题是调查人员之间以及美国人和罗马尼亚人之间合作讨论的中心焦点。从多个角度进行深入的讨论是必要的，以进行道德上合理和科学意义的研究。
The Bucharest Early Intervention Project (BEIP) is the first ever randomized controlled trial of foster care as an alternative to institutional care for young children. It involved a collaboration between American investigators and Romanian health and child protection professionals. We present a brief description of the Romanian context and the project itself before discussing a number of ethical issues raised by the project. Organized around a discussion of exploitation, risk/benefit ratio, and cultural sensitivity, we evaluate a number of ethical issues involved in the BEIP using the Ethical Clinical Research Framework and the Fair Benefits Framework. Based on this review, we conclude that notwithstanding challenging ethical dilemmas, the benefits of the project outweighed its risks. Throughout the planning and implementation of the project, ethical issues were a central focus of discussion among the investigators and in the collaboration between Americans and Romanians. Thoughtful discussions from multiple perspectives are necessary to conduct research that is ethically sound and scientifically meaningful.