Bmc Medical Genetics Genome-wide Association of Sleep and Circadian Phenotypes
Bmc Medical Genetics Genome-wide Association of Sleep and Circadian Phenotypes
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通讯作者：
D. Gottlieb;George T. O’ Connor;J. Wilk;T. O 'connor
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作者：
D. Gottlieb;George T. O’ Connor;J. Wilk;T. O 'connor
背景：许多研究表明遗传因素对嗜睡和昼夜节律有影响。睡眠心脏健康研究收集了2848名心脏研究后代队列参与者的睡眠习惯和嗜睡问卷数据。超过700名参与者使用Affysse100K SNP基因芯片进行基因分型，为评估这些性状的遗传连锁和关联提供了独特的机会。
Background: Numerous studies suggest genetic influences on sleepiness and circadian rhythms. The Sleep Heart Health Study collected questionnaire data on sleep habits and sleepiness from 2848 Framingham Heart Study Offspring Cohort participants. More than 700 participants were genotyped using the Affymetrix 100K SNP GeneChip, providing a unique opportunity to assess genetic linkage and association of these traits.