Depressive symptoms and mortality in elderly persons.
Depressive symptoms and mortality in elderly persons.
复制标题
老年人的抑郁症状和死亡率。
DOI：
10.1093/geronj/47.2.s80
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发表时间：
1992
期刊：
影响因子：
--
通讯作者：
Yang,CY
中科院分区：
文献类型：
--
作者：
Thomas,C;Kelman,HR;Kennedy,GJ;Ahn,C;Yang,CY
关于老年社区人群中抑郁症和死亡率之间的关系的研究得出了相互矛盾的结果，尽管在对老年精神病患者的研究中经常发现这种联系。这些不同的结果可能是由于抑郁症的测量方法、研究人群、分析中的协变量或样本损耗的不同所致。在这项针对城市社区老年居民的研究中，抑郁症状在两个时间点进行了测量。人们被归类为持续无症状(N-N)、有紧急症状(N-D)、缓解(D-N)或持续有症状(D-D)。在多变量Cox回归模型中，抑郁症状、社会人口学特征以及健康、功能状态、慢性疾病的数量和社会支持的改变的衡量标准与死亡率之间的关系被检验。尽管没有发现抑郁症症状与死亡时间有关，但老年人、健康和功能状态下降的人以及男性在三年的随访中死亡的相对风险更大。
Studies on the relationship between depression and mortality in elderly community populations have yielded contradictory findings, although an association frequently is found in studies of elderly psychiatric patients. These different results may be due to differences in the measures of depression, the populations under study, the covariates in the analysis, or to sample attrition. In this study of elderly residents of an urban neighborhood, depressive symptoms are measured at two time points. People are classified as consistently nonsymptomatic (N-N), with emergent symptoms (N-D), in remission (D-N), or persistently symptomatic (D-D). Symptoms of depression, sociodemographic characteristics, and measures of changes in health, functional status, number of chronic medical conditions, and social support are examined in relation to mortality in multivariate cox regression models. Although symptoms of depression are not found to be related to time-to-death, older people, those with declines in health and functional status, and men have greater relative risks of mortality over a three-year follow-up