Rice GIBBERELLIN INSENSITIVE DWARF1 is a gibberellin receptor that illuminates and raises questions about GA signaling
Rice GIBBERELLIN INSENSITIVE DWARF1 is a gibberellin receptor that illuminates and raises questions about GA signaling
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DOI：
10.1105/tpc.105.039958
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发表时间：
2006-02-01
期刊：
影响因子：
11.6
通讯作者：
Olszewski, NE
中科院分区：
文献类型：
--
作者：
Hartweck, LM;Olszewski, NE
最近，随着Ueguchi-Tanaka等人(2005)的报道，赤霉素(GAs)加入了已知受体蛋白的植物激素名单，水稻的赤霉素不敏感的DWARF1(GID1)蛋白具有人们期待已久的GA受体的预期特性。这一令人兴奋的发现不仅为GA信号转导途径的谜团提供了重要的新线索，也提出了新的问题，并质疑了一些关于该途径拓扑结构的长期假设。GA是一种四环二萜类化合物，通过促进萌发、下胚轴伸长、相变、根、叶、茎和果实的生长、叶片的绿化、开花以及花和种子的发育，在植物生活史的所有阶段发挥作用。此外，它们还与分生组织功能有关，最近被证明抑制细胞分裂素的作用(Greenboim-Wainberg等人，2005年)。GA作用、生物合成和信号转导是最近几篇综述的主题(Sponsel，1995；Olszewski等人，2002；Sakamoto等人，2004；Sun和Gubler，2004；Swain和Singh，2005)。在本文中，我们总结了发现GID1作为GA受体的步骤，并讨论了关于GA信号转导的剩余问题。
Recently, gibberellins (GAs) joined the list of plant hormones with a known receptor protein with the report by Ueguchi-Tanaka et al.(2005) that the GIBBERELLIN INSENSITIVE DWARF1 (GID1) protein of rice has the expected properties of the long-sought GA receptor. This exciting discovery not only provides a major new piece to the puzzle of the GA signal transduction pathway but also raises new questions and calls into question some long-held assumptions concerning the topology of the pathway.GAs are tetracyclic diterpenoids that act at all stages in the plant life cycle by promoting germination, hypocotyl elongation, phase transitions, root, leaf, stem, and fruit growth, greening of leaves, flowering, and flower and seed development. In addition, they have been implicated in meristem function and recently have been shown to inhibit cytokinin action (Greenboim-Wainberg et al., 2005). GA action, biosynthesis, and signaling have been the subject of several recent reviews (Sponsel, 1995; Olszewski et al., 2002; Sakamoto et al., 2004; Sun and Gubler, 2004; Swain and Singh, 2005). In this essay, we summarize the steps leading to the discovery that GID1 functions as a GA receptor and discuss remaining questions concerning GA signal transduction.