Long-term effects of dieting on resting metabolic rate in obese outpatients.
Long-term effects of dieting on resting metabolic rate in obese outpatients.
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DOI：
10.1001/jama.1990.03450060053028
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发表时间：
1990-08
期刊：
影响因子：
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通讯作者：
T. Wadden;G. D. Foster;K. A. Letizia;J. L. Mullen
中科院分区：
文献类型：
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作者：
T. Wadden;G. D. Foster;K. A. Letizia;J. L. Mullen
人们越来越担心节食可能会对代谢率产生不利影响，并加剧控制体重的努力。在这项研究中，我们测量了18名肥胖女性在48周内9次的静息代谢率，她们被随机分配到两种饮食条件中的一种。9名患者在整个48周期间每天摄入约5021千焦(1200千卡/天)，而另外9名患者在前17周中有16周每天摄入1757千焦(420千卡/天)的饮食，其余治疗期间采用传统的减量饮食。所有患者都增加了体力活动，主要是通过步行。在最初的5周内，代谢率的下降是体重相对下降的两倍多。48周时，两组患者的代谢率分别下降9.4%±4.0%和8.3%±2.2%，体重分别下降16.6%±2.7%和19.5%±2.7%。因此，无论哪种饮食方案，结合适度的体力活动，都与长期静息代谢率的降低没有关联，后者超过了实现较低体重所预期的降幅。
There is growing concern that dieting may adversely affect the metabolic rate and exacerbate efforts to control weight. In this study we measured the resting metabolic rate nine times over 48 weeks in 18 obese women (108.0 +/- 3.1 kg) who were randomly assigned to one of two dietary conditions. Nine patients consumed approximately 5021 kJ/d (1200 kcal/d) throughout the 48 weeks, while the other nine consumed a 1757-kJ/d (420-kcal/d) diet for 16 of the first 17 weeks and a conventional reducing diet for the remainder of treatment. All patients increased their physical activity, primarily by walking. During the first 5 weeks, the fall in metabolic rate was more than double the relative reduction in weight. By contrast, at week 48, the metabolic rate of patients in the two conditions was reduced by 9.4% +/- 4.0% and 8.3% +/- 2.2%, respectively, while weight was reduced by 16.6% +/- 2.7% and 19.5% +/- 2.7%, respectively. Thus, neither dietary regimen, combined with modest physical activity, was associated with long-term reductions in resting metabolic rate that exceeded decreases anticipated with the achievement of a lower body weight.