Predictions and measurements of scattering and absorption over broad wavelength ranges in tissue phantoms
Predictions and measurements of scattering and absorption over broad wavelength ranges in tissue phantoms
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DOI：
10.1364/ao.36.000949
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发表时间：
1997-02-01
期刊：
影响因子：
1.9
通讯作者：
Bigio, IJ
中科院分区：
文献类型：
--
作者：
Mourant, JR;Fuselier, T;Bigio, IJ
从米氏理论的预测，从近紫外到近红外的组织中的散射的波长依赖性进行了讨论，并与实验组织幻影。对于大的纤维分离，它示出，快速，同时测量的弹性散射信号的几个纤维分离可以产生的吸收系数和减少的散射系数。利用这些信息，可以估计散射颗粒的大小，这是针对Intraperoid完成的。在较小的源检测器分离的测量支持米氏理论计算，表明弹性散射测量的灵敏度的形态特征，如散射体的大小，增强时，源和检测器之间的距离纤维是小的。(C)1997年美国光学学会
Predictions from Mie theory regarding the wavelength dependence of scattering in tissue from the near UV to the near IR are discussed and compared with experiments on tissue phantoms. For large fiber separations it is shown that rapid, simultaneous measurements of the elastic scatter signal for several fiber separations can yield the absorption coefficient and reduced scattering coefficient. With this information, the size of the scattering particles can be estimated, and this is done for Intralipid. Measurements made at smaller source detector separations support Mie theory calculations, demonstrating that the sensitivity of elastic scatter measurements to morphological features, such as scatterer size, is enhanced when the distance between the source and detector fibers is small. (C) 1997 Optical Society of America