Vesicular transport across the fungal cell wall.
Vesicular transport across the fungal cell wall.
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DOI:
10.1016/j.tim.2008.12.005
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发表时间:
2009-04
影响因子:
15.9
通讯作者:
Rodrigues ML
中科院分区:
文献类型:
--
作者:
Casadevall A;Nosanchuk JD;Williamson P;Rodrigues ML
Recent findings indicate that fungi use vesicular transport to deliver substances across their cell walls. Fungal vesicles are similar to mammalian exosomes and could originate from cytoplasmic multivesicular bodies. Vesicular transport enables the export of large molecules across the cell wall, and vesicles contain lipids, proteins and polysaccharides, many of which are associated with virulence. Concentration of fungal products in vesicles could increase their efficiency in food acquisition and/or delivering potentially noxious substances to other cells, such as amoebae or phagocytes. The discovery of vesicular transport in fungi opens many new avenues for investigation in basic cell biology and pathogenesis.
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