Is Almond Consumption More Effective Than Reduced Dietary Saturated Fat at Decreasing Plasma Total Cholesterol and LDL-c Levels? A Theoretical Approach.
Is Almond Consumption More Effective Than Reduced Dietary Saturated Fat at Decreasing Plasma Total Cholesterol and LDL-c Levels? A Theoretical Approach.
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在降低血浆总胆固醇和低密度脂蛋白胆固醇水平方面，食用杏仁是否比减少膳食饱和脂肪更有效？
DOI：
10.1155/2012/265712
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发表时间：
2012
影响因子：
2.2
通讯作者：
Kim,ArnoldD
中科院分区：
文献类型：
--
作者：
Ortiz,RudyM;Garcia,Steven;Kim,ArnoldD
高胆固醇血症可能是过量膳食饱和脂肪酸 (SFA) 的结果，而补充杏仁的饮食可以改善血脂状况。然而，膳食 SFA 和补充杏仁的饮食对血浆总胆固醇 (pTC) 和低密度脂蛋白 (pLDL-c) 浓度的差异和独立影响尚未直接比较，也没有得到很好的描述。我们回顾了现有数据，构建了多元回归分析，从理论上评估了相对杏仁摄入量 (RAI) 和膳食 SFA 对降低 pTC 和 pLDL-c 浓度的影响。检测到 RAI 与平均 pTC 变化百分比（R= 0.776；P= 0.005）以及 RAI 与平均 pLDL-c 变化百分比（R= 0.818；P= 0.002）之间存在很强的负相关性。平均膳食 SFA 的百分比变化与平均 pTC 和平均 pLDL-c 的百分比变化之间的关系较弱，并且仅对 pLDL-c 有意义。多元回归分析表明 pTC（R= 0.804；P= 0.016）和 pLDL-c（R= 0.855；P= 0.005）的相关强度略有改善。模型表明，与膳食 SFA 的减少相比，RAI 的增加在更大程度上有助于 pTC 和 pLDL-c 的减少，但同时膳食 SFA 的减少应该会进一步改善血脂状况。
Hypercholesterolemia can be a consequence of excessive dietary saturated fatty acid (SFA), while almond‐supplemented diets can improve lipid profiles. However, the differential and independent impacts of dietary SFA and almondsupplemented diets on plasma total cholesterol (pTC) and low‐density lipoprotein (pLDL‐c) concentrations have not been directly compared and are not well described. We reviewed the available data to construct multiple regression analyses to theoretically assess the impact of relative almond intake (RAI) and dietary SFA on reducing pTC and pLDL‐c concentrations. Strong, negative correlations between RAI and percent change in mean pTC (R= 0.776;P= 0.005) and RAI and percent change in mean pLDL‐c (R= 0.818;P= 0.002) were detected. The relationships between percent change in mean dietary SFA, and percent change in mean pTC and mean pLDL‐c were weaker and only significant for pLDL‐c. The multiple regression analyses demonstrated modest improvements in the strength of the correlations for both pTC (R= 0.804;P= 0.016) and pLDL‐c (R= 0.855;P= 0.005). The models suggest that the increase in RAI contributes to the reduction in pTC and pLDL‐c to a greater extent than a reduction in dietary SFA, but a simultaneous decrease in dietary SFA should further improve lipid profiles.