The identification of flavonoids as glycosides in human plasma
The identification of flavonoids as glycosides in human plasma
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DOI：
10.1016/s0014-5793(96)01442-1
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发表时间：
1997-01-13
期刊：
影响因子：
3.5
通讯作者：
RiceEvans, CA
中科院分区：
文献类型：
--
作者：
Paganga, G;RiceEvans, CA
本研究描述了黄酮类化合物的吸收及其在人血浆中以糖基化形式存在的证据，通过采用光电二极管阵列检测的HPLC分析，同时检测到Rynocaine和其他槲皮素糖苷、根皮苷以及花青素，此外，还鉴定了具有橙酮家族光谱特性的化合物洗脱，结果表明根皮素和槲皮素作为糖苷从饮食中被吸收，多酚在来自未补充的人的血浆中以0.5-1.6 μ M范围内的个体水平被检测到。
This study describes evidence for the absorption of flavonoids and their presence in human plasma in the glycosylated form by HPLC analysis with photodiode array detection, Rutin and other quercetin glycosides, phloridzin, as well as an anthocyanin are detected simultaneously, In addition, a compound eluting with the spectral properties of the aurone family is identified, The results reveal that phloretin and quercetin are absorbed from the diet as glycosides, The polyphenols are detected in plasma from non-supplemented humans at individual levels in the range 0.5-1.6 mu M.