Respiratory Syncytial Virus Seasonality - United States, 2014-2017
Respiratory Syncytial Virus Seasonality - United States, 2014-2017
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DOI：
10.15585/mmwr.mm6702a4
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发表时间：
2018-01-19
影响因子：
33.9
通讯作者：
Haynes, Amber
中科院分区：
文献类型：
--
作者：
Rose, Erica Billig;Wheatley, Alexandra;Haynes, Amber
关于这个话题我们已经知道了什么？在美国大部分地区，呼吸道合胞病毒（RSV）的流行季节从秋季持续到春季，但每年和不同的地理区域有所不同。本报告使用了一种新的统计方法，分析了向国家呼吸道和肠道病毒监测系统（NREVSS）报告的聚合酶链反应实验室检测结果，以确定最近三个季节（2014-2017年）全国和各地区的RSV季节性。在全国范围内，从2014年7月5日结束的一周持续到2017年7月1日，中位RSV发作发生在第41周（10月中旬），持续31周直至第18周（5月初）。全国平均峰值出现在第5周（2月初）。2014-17年流感季的发病时间比2012-2014年流感季（10月上旬至中旬与10月下旬至11月上旬）提前约2周，这是使用抗原数据确定的。对公共卫生实践有何影响？RSV季节性数据可以指导诊断检测，并为当前可用的免疫预防产品的管理（如有指征）以及临床试验的时间安排和目前正在开发的疫苗和免疫预防产品的未来评估提供决策依据。
What is already known about this topic?For most of the United States, the respiratory syncytial virus (RSV) season lasts from fall through spring but varies from year to year and by geographic region.What is added by this report?This report uses a new statistical method that analyzes polymerase chain reaction laboratory detections reported to the National Respiratory and Enteric Virus Surveillance System (NREVSS) to determine RSV seasonality nationally and by region for three recent seasons (2014-2017). Nationally, lasting from the week ending July 5, 2014 through July 1, 2017, the median RSV onset occurred at week 41 (mid-October), and lasted 31 weeks until week 18 (early May). The median national peak occurred at week 5 (early February). Onsets for the 2014-17 seasons occurred approximately 2 weeks earlier than did those for the 2012-2014 seasons (early to mid-October versus late October to early November),which were determined using antigen data. What are the implications for public health practice?RSV seasonality data can guide diagnostic testing and inform policy decisions regarding administration of currently available immunoprophylaxis products, when indicated, and the timing of clinical trials and future evaluations of vaccines and immunoprophylaxis products currently under development.