THE ROLE OF THE BASAL GANGLIA IN CONTROLLING A MOVEMENT INITIATED BY A VISUALLY PRESENTED CUE
THE ROLE OF THE BASAL GANGLIA IN CONTROLLING A MOVEMENT INITIATED BY A VISUALLY PRESENTED CUE
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DOI：
10.1016/0006-8993(80)91003-3
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发表时间：
1980-01-01
期刊：
影响因子：
2.9
通讯作者：
MURPHY, JT
中科院分区：
文献类型：
--
作者：
ALDRIDGE, JW;ANDERSON, RJ;MURPHY, JT
研究了视觉刺激对尾状核和苍白球单个神经元的影响，视觉刺激是记录部位对侧前肢开始跟踪运动的线索。研究了这些结构中单个神经元的活动与运动起始之间的关系。制备猴[Macaca arctoides，4]用于单个神经元的慢性记录。这些动物被训练来执行跟踪任务，该任务涉及在视觉提示开始时手腕的弯曲和伸展。大部分神经元的活动与任务相关，苍白球的比例大于尾状核。大多数相关神经元在肌肉活动和随后的运动开始后被激活。这些细胞不太可能参与运动的启动。结果不排除移动执行中的角色。许多细胞只对视觉线索试验中的某些特定条件做出反应，这一事实表明，来自其他大脑区域的高度加工的视觉信息对这些细胞产生了影响。
The effects on single neurons in caudate nucleus and globus pallidus of a visual stimulus, which is a cue to begin a tracking movement involving the forelimb on the side contralateral to the recording site were studied. The relationship between activity of single neurons in these structures and movement initiation was studied. Monkeys [Macaca arctoides, 4] were prepared for chronic recording of single neurons. The animals were trained to perform a tracking task that involved flexion and extension of the wrist at the onset of visual cue. The activities of a large proportion of neurons examined were correlated with the task, the proportion being greater in globus pallidus than in caudate nucleus. The majority of correlated neurons were activated after the onset of muscle activity and subsequent movement. It is unlikely that these cells were involved in movement initiation. A role in movement execution is not excluded by the results. The fact that many cells were responsive only to certain specific conditions of the visual cue trial suggests an influence on these cells by highly processed visual information from other brain areas.