BASAL AND SQUAMOUS-CELL CARCINOMA OF THE EYELIDS AND THEIR TREATMENT BY RADIOTHERAPY
BASAL AND SQUAMOUS-CELL CARCINOMA OF THE EYELIDS AND THEIR TREATMENT BY RADIOTHERAPY
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DOI：
10.1016/0360-3016(84)90023-3
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发表时间：
1984-01-01
影响因子：
7
通讯作者：
PAYNE, DG
中科院分区：
文献类型：
--
作者：
FITZPATRICK, PJ;THOMPSON, GA;PAYNE, DG
共1166例眼睑肿瘤接受了20-60戈伊[gray]单次或分次照射治疗。5年肿瘤控制率基底细胞癌为95%，鳞状细胞癌为93.3%。放疗在原发病例和术后复发病例中同样成功。放疗后复发通过手术或进一步放疗进行管理。美容和功能结果通常是优秀的，并易于接受的大多数患者。总体并发症发生率为9.6%，其中不到1/2被评定为严重;这些问题主要发生在破坏正常组织的大肿瘤中。仅14例（1.2%）患者死亡与肿瘤有关。约1/2的患者接受35戈伊分5次照射，1/4的患者接受20-22.5戈伊单次照射，1/4的患者接受42.5-60戈伊分10-30次照射，2-6 wk。放射治疗是眼睑肿瘤的一种安全和经济有效的治疗方法。
A total of 1166 tumors of the eyelids were treated by single or fractionated exposures to doses of 20-60 Gy [gray]. The 5 yr tumor control rate was 95% for basal cell and 93.3% for squamous cell carcinoma. Irradiation was equally successful in primary cases and in those recurrent following surgery. Recurrence following irradiation was managed by surgery or further irradiation. The cosmetic and functional results were generally excellent and readily accepted by most patients. The overall complication rate was 9.6% with fewer than 1/2 rated as serious; these problems mainly occurred with large tumors that had destroyed normal tissues. In only 14 (1.2%) patients was death related to the tumor. Approximately 1/2 of the patients received a dose of 35 Gy in 5 daily fractions, 1/4, 20-22.5 Gy in a single exposure and the others with larger tumors 42.5-60 Gy in 10-30 exposures in 2-6 wk. Radiotherapy is a safe and cost effective treatment for eyelid tumors.