ASSESSMENT OF NEUTROPHIL CHEMOTAXIS AND RANDOM MIGRATION IN CHILDHOOD - COMPARISON BETWEEN LEADING-FRONT AND LOWER SURFACE COUNT METHODS

ASSESSMENT OF NEUTROPHIL CHEMOTAXIS AND RANDOM MIGRATION IN CHILDHOOD - COMPARISON BETWEEN LEADING-FRONT AND LOWER SURFACE COUNT METHODS
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DOI:
10.1136/adc.55.4.296
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发表时间:
1980-01-01
影响因子:
5.2
通讯作者:
THOMPSON, EN
THOMPSON, EN
中科院分区:
医学2区
文献类型:
--
作者:
ALNAKEEB, S;THOMPSON, EN

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本文对65例健康儿童和18例正常成人的神经细胞趋化性和随机游走进行了研究。所使用的方法,领先的前沿技术,是更准确和重现性比低表面计数方法。15岁以下儿童的趋化性与成人不同。这种年龄效应在6岁以下儿童中最为明显,尤其是2岁以下儿童。当研究儿童期的趋化性时,应与年龄匹配的对照组进行比较。
Neutrophil chemotaxis and random migration were studied in 65 healthy children and 18 normal adults. The method used, the leading-front technique, was more accurate and reproducible than the lower surface count method. Chemotaxis in children under 15 yr differed from that in adults. This age effect was most pronounced in those less than 6 yr, particularly in those less than 2 yr. When investigating chemotaxis in childhood, comparisons with age-matched controls should be made.