Four New Kaurane Diterpenoids from the Chinese Liverwort Jungermannia comata Nees.
Four New Kaurane Diterpenoids from the Chinese Liverwort Jungermannia comata Nees.
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来自中国地衣Jungermannia comata Nees 的四种新贝壳杉烷二萜类化合物。
DOI：
10.1002/cbdv.201600123
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发表时间：
2016
影响因子：
2.9
通讯作者：
Hongxiang Lou
中科院分区：
文献类型：
--
作者：
Ruijuan Li;Song Wang;Gang Li;Jinchuan Zhou;Jiaozhen Zhang;Youming Zhang;Guosheng Shi;Hongxiang Lou
在我们继续从地钱植物中寻找新的生物活性化合物的过程中，从中国地钱植物中分离得到了4个新的狗牙烷型二萜化合物：(6β)-kaur-16-烯-6，9-二醇(1)，(6β，12β)-kaur-16-烯-6，9，12-三醇(2)，(6β)-kaur-16-烯-5，6，9-三醇(3)和kaur-16-烯-9，19-二醇(4)。还得到了5个已知的角叉烷型二萜化合物(5-9)和4个已知的粗枝环烷型二萜化合物(10-13)。根据波谱数据明确地确定了新化合物的结构。通过比较实验和计算的电子圆二色谱，确定了化合物1的绝对构型。
In our continuing program to find new bioactive compounds from the Chinese liverworts, four new kaurane‐type diterpenoids, (6β)‐kaur‐16‐ene‐6,9‐diol (1), (6β,12β)‐kaur‐16‐ene‐6,9,12‐triol (2), (6β)‐kaur‐16‐ene‐5,6,9‐triol (3), and kaur‐16‐ene‐9,19‐diol (4), have been isolated from the Chinese liverwortJungermannia comataNees. Five known kaurane‐type diterpenoids (5–9) and four known trachylobane‐type diterpenoids (10–13) were also obtained. The structures of the new compounds were established unequivocally on the basis of spectroscopic data. The absolute configuration of compound1was established by comparing experimental and calculated electronic circular dichroism spectra.