The Glycan Structure Dictionary-a dictionary describing commonly used glycan structure terms.
The Glycan Structure Dictionary-a dictionary describing commonly used glycan structure terms.
复制标题
聚糖结构词典 - 描述常用聚糖结构术语的词典。
DOI：
10.1093/glycob/cwad014
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发表时间：
2023
期刊：
影响因子：
4.3
通讯作者：
Mazumder,Raja
中科院分区：
文献类型：
--
作者：
Vora,Jeet;Navelkar,Rahi;Vijay-Shanker,K;Edwards,Nathan;Martinez,Karina;Ding,Xiying;Wang,Tianyi;Su,Peng;Ross,Karen;Lisacek,Frederique;Hayes,Catherine;Kahsay,Robel;Ranzinger,Rene;Tiemeyer,Michael;Mazumder,Raja
最近糖生物学的技术进步导致了大量数据的涌入和许多描述糖科学发现的论文的发表。然而，用于描述多糖结构特征的术语没有标准化，使得协调生物分子数据库中的数据变得困难，阻碍了跨研究信息的获取，并阻碍了文本挖掘和整理工作。为了解决这一缺点，已开发了作为参考词典的糖链结构词典，以提供广泛使用的糖链术语的标准化列表，该列表可帮助对出版物中描述的糖链结构进行整理和作图。目前，该词典有190个糖链结构术语，297个同义词链接到3332种出版物。要将一个术语收录在词典中，它必须出现在至少两个同行评议的出版物中。还提供了GlyTouCan、GlycoMotif和其他相关数据库和资源的同义词、注释和交叉引用(如果可用)。这项工作的目的是促进生物识别，协助文本挖掘工具的开发，改进搜索的一致性，以及浏览糖信息学资源的能力，并帮助绘制糖结构与功能和疾病的图谱。随着时间的推移，预计作者将使用这些术语来描述他们手稿中的多糖结构。还为研究人员提供了一种机制，以提交可能合并的条款。这本词典可以在https://wiki.glygen.org/Glycan_structure_dictionary.上找到
Recent technological advances in glycobiology have resulted in a large influx of data and the publication of many papers describing discoveries in glycoscience. However, the terms used in describing glycan structural features are not standardized, making it difficult to harmonize data across biomolecular databases, hampering the harvesting of information across studies and hindering text mining and curation efforts. To address this shortcoming, the Glycan Structure Dictionary has been developed as a reference dictionary to provide a standardized list of widely used glycan terms that can help in the curation and mapping of glycan structures described in publications. Currently, the dictionary has 190 glycan structure terms with 297 synonyms linked to 3,332 publications. For a term to be included in the dictionary, it must be present in at least 2 peer-reviewed publications. Synonyms, annotations, and cross-references to GlyTouCan, GlycoMotif, and other relevant databases and resources are also provided when available. The purpose of this effort is to facilitate biocuration, assist in the development of text mining tools, improve the harmonization of search, and browse capabilities in glycoinformatics resources and help to map glycan structures to function and disease. It is also expected that authors will use these terms to describe glycan structures in their manuscripts over time. A mechanism is also provided for researchers to submit terms for potential incorporation. The dictionary is available at https://wiki.glygen.org/Glycan_structure_dictionary.