Prevalence and clinical outcomes of young breast cancer (YBC) patients according to intrinsic breast cancer subtypes: Single institutional experience in Korea
Prevalence and clinical outcomes of young breast cancer (YBC) patients according to intrinsic breast cancer subtypes: Single institutional experience in Korea
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DOI：
10.1016/j.breast.2015.01.012
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发表时间：
2015-06-01
期刊：
影响因子：
3.9
通讯作者：
Im, Young-Hyuck
中科院分区：
文献类型：
--
作者：
Park, Yeon Hee;Lee, Su Jin;Im, Young-Hyuck
我们研究的目的是根据内在亚型全面调查和鉴定年轻乳腺癌（YBC）的临床病理特征和长期结果。我们分析了 2000 年至 2007 年间 2844 名被诊断患有浸润性乳腺癌的女性的临床和病理特征，以及按诊断时年龄划分的治疗结果。患者的中位年龄为46岁（范围21-83岁），我们将他们分为三个年龄组：50岁（第3组）。中位随访100个月期间，5年无复发生存率（RFSR）和总生存率（OSR）分别为90.8%和94.6%。 10 年估计 RFSR 和 OSR 分别为 81.9% 和 86.9%。 TN 亚型的预后似乎并不比第 1 组中的其他亚型差。仅在第 1 组中（
The purpose of our study was to investigate and identify comprehensively the clinicopathological features and long-term outcome of young breast cancer (YBC) according to intrinsic subtype. We analyzed clinical and pathological characteristics of 2844 women who were diagnosed with invasive breast cancer from 2000 to 2007 and the treatment outcomes by age at diagnosis. The median age of the patients was 46 years (range, 21-83 years), and we divided them into three age group: 50 years (Group 3). During a median follow-up of 100 months, the 5-year recurrence-free survival rate (RFSR) and overall survival rate (OSR) were 90.8% and 94.6%, respectively. The 10-year estimated RFSR and OSR were 81.9% and 86.9%, respectively. The prognosis of TN subtype appeared not to be worse than that of other subtypes in Group 1. In Group 1 alone (