Comparison of the diagnostic value of FDG-PET/CT and axillary ultrasound for the detection of lymph node metastases in breast cancer patients
Comparison of the diagnostic value of FDG-PET/CT and axillary ultrasound for the detection of lymph node metastases in breast cancer patients
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DOI：
10.1258/ar.2012.110635
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发表时间：
2012-12-01
期刊：
影响因子：
1.3
通讯作者：
Heusner, Till A.
中科院分区：
文献类型：
--
作者：
Riegger, Carolin;Koeninger, Angela;Heusner, Till A.
背景：FDG-PET/CT越来越多地用于乳腺癌分期。其诊断准确性相比，超声作为标准的非侵入性成像方式评价腋窝淋巴结尚未evaluated.Purpose：回顾性比较全剂量，静脉造影剂增强FDG-PET/CT和超声检测乳腺癌患者淋巴结转移的诊断价值。材料和方法：90例原发性乳腺癌患者（1例双侧癌患者）（89例女性，1例男性;平均年龄55.5 ± 16.6岁）接受了全身FDG-PET/CT和腋窝超声检查。评价同侧腋窝（n = 91）的转移性扩散。计算两种方法的敏感性、特异性、阳性预测值（PPV）、阴性预测值（NPV）和准确性。用McNemar检验比较其敏感性和准确性（P
Background: FDG-PET/CT is increasingly being used for breast cancer staging. Its diagnostic accuracy in comparison to ultrasound as the standard non-invasive imaging modality for the evaluation of axillary lymph nodes has yet not been evaluated.Purpose: To retrospectively compare the diagnostic value of full-dose, intravenously contrast-enhanced FDG-PET/CT and ultrasound for the detection of lymph node metastases in breast cancer patients.Material and Methods: Ninety patients (one patient with a bilateral carcinoma) (89 women, one man; mean age, 55.5 +/- 16.6 years) suffering from primary breast cancer underwent whole-body FDG-PET/CT and axillary ultrasound. The ipsilateral axillary fossa (n = 91) was evaluated for metastatic spread. The sensitivity, specificity, the positive predictive value (PPV), negative predictive value (NPV), and accuracy of both methods were calculated. The sensitivity and accuracy were statistically compared using the McNemar Test (P