Large improvements in major cardiovascular risk factors in the population of northern Sweden: the MONICA study 1986-2009
Large improvements in major cardiovascular risk factors in the population of northern Sweden: the MONICA study 1986-2009
复制标题
DOI：
10.1111/j.1365-2796.2010.02312.x
复制
发表时间：
2011-02-01
影响因子：
11.1
通讯作者：
Eliasson, M.
中科院分区：
文献类型：
--
作者：
Eriksson, M.;Holmgren, L.;Eliasson, M.
Eriksson M，Holmgren L，Janlert U，Jansson J-H，Lundblad D，Stegmayr B，Soderberg S，Eliasson M（Department of Public Health and Clinical Medicine，Umea University，Umea; Research Department，诺尔博滕县理事会，卢莱亚; Department of Medicine，斯凯莱夫泰亚Hospital，斯凯莱夫泰亚; Department of Medicine，Sunderby Hospital，卢莱亚; and National Board of Health and Welfare，斯德哥尔摩，瑞典）.瑞典北方人群主要心血管危险因素的大幅改善：1986-2009年MONICA研究J Intern Med 2011; 269：219- 231. Objectives.20世纪80年代以来，瑞典的心血管疾病发病率迅速下降。我们探索了1986年至2009年间瑞典北方主要心血管危险因素的变化。设计。自1986年以来，使用世界卫生组织MONICA项目的程序在瑞典北方进行了六次人口调查。1986年和1990年人口年龄范围为25-64岁，1994年为25-74岁。采用广义线性模型对趋势进行分析。结果：共有10 586名受试者被纳入调查。1986年至2009年期间，25-64岁的女性血压下降4.9/3.9 mmHg，男性血压下降1.8/1.5 mmHg。在65-74岁的男性和女性中，1994年至2009年下降了12.6/6.1 mmHg。从1994年起，降低血压药物的使用有所增加，特别是在老年人中。1986年至2009年，吸烟率下降了一半; 2009年，11%的妇女和9%的男子吸烟。胆固醇水平下降了0.9 mmol L-1的年轻年龄组（25-64岁），降脂药的使用从1994年开始增加。在25-64岁的受试者中，2009年有五分之一的人肥胖，是1986年的两倍，体重指数（BMI）增加了1.5 kg m-2，相当于体重增加了4 kg。自2004年以来，BMI没有进一步增加。糖尿病的患病率在1986年至2009年之间没有变化。在研究期间，所有年龄组中接受过大学教育的比例均显著增加，尤其是女性。结论：1986年至2009年期间，在瑞典北方的主要心血管危险因素中观察到显著改善。
Eriksson M, Holmgren L, Janlert U, Jansson J-H, Lundblad D, Stegmayr B, Soderberg S, Eliasson M (Department of Public Health and Clinical Medicine, Umea University, Umea; Research Department, Norrbotten County Council, Lulea; Department of Medicine, Skelleftea Hospital, Skelleftea; Department of Medicine, Sunderby Hospital, Lulea; and National Board of Health and Welfare, Stockholm, Sweden). Large improvements in major cardiovascular risk factors in the population of northern Sweden: the MONICA study 1986-2009. J Intern Med 2011; 269: 219-231.Objectives.The incidence of cardiovascular disease has declined rapidly in Sweden since the 1980s. We explored changes in major cardiovascular risk factors in northern Sweden between 1986 and 2009.Design.Since 1986, six population surveys have been carried out in northern Sweden using procedures of the World Health Organization MONICA project. The population age range was 25-64 years in 1986 and 1990, and 25-74 years from 1994. Trends were analysed using generalized linear models.Results.A total of 10 586 subjects were included in the surveys. Blood pressure decreased by 4.9/3.9 mmHg in women and 1.8/1.5 mmHg in men aged 25-64 years between 1986 and 2009. In men and women aged 65-74 years, the decrease was 12.6/6.1 mmHg between 1994 and 2009. From 1994, the use of blood pressure-lowering drugs increased, particularly among the older subgroup. The prevalence of smoking halved between 1986 and 2009; 11% of women and 9% of men were smokers in 2009. Cholesterol levels decreased by 0.9 mmol L-1 in the younger age group (25-64 years), and the use of lipid-lowering agents increased from 1994. Among subjects aged 25-64 years, one in five was obese in 2009, which was twice as many as in 1986, and body mass index (BMI) increased by 1.5 kg m-2, corresponding to an increase in weight of 4 kg. There was no further increase in BMI from 2004. The prevalence of diabetes did not change between 1986 and 2009. The proportion that received a university education increased markedly in all age groups, especially in women, during the study period.Conclusions.Significant improvements were observed in major cardiovascular risk factors in northern Sweden between 1986 and 2009.