The effect of solvent and pressure on polycaprolactone solutions for particle and fibre formation
The effect of solvent and pressure on polycaprolactone solutions for particle and fibre formation
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DOI：
10.1016/j.eurpolymj.2022.111300
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发表时间：
2022-05-31
影响因子：
6
通讯作者：
Edirisinghe, Mohan
中科院分区：
文献类型：
--
作者：
Altun, Esra;Ahmed, Jubair;Edirisinghe, Mohan
聚己内酯(PCL)是一种广泛使用的材料，用于解决全球范围内的健康问题。形成的微米或纳米尺寸的PCL颗粒和纤维得益于较高的表面积与体积比，在这些应用中具有很高的价值，因此总是推动实现更小的直径。电液动力(EHD)技术一直处于聚合物生物材料生产的前沿，而加压回转(PG)也因其快速旋转类似纤维的能力而增强了可能性。在本工作中，通过改变EHD和PG系统的关键操作参数和PCL溶液的性质，分别制备了PCL微粒和纤维。首先，用不同的二元溶剂体系电喷涂形成PCL微粒，然后用各种单一溶剂和预优化的二元溶剂体系生产加压回转纤维。正如预期的那样，二元体系的使用改变了颗粒的形态和直径，而压力的增加和不同溶剂的使用极大地影响了所得纤维的特性。研究发现，PCL的形态高度依赖于所使用的溶剂和操作参数。
Polycaprolactone (PCL) is a widely used material in many applications to tackle health problems worldwide. Formed micro- or nanosized PCL particles and fibres benefit from a higher surface area to volume ratio and are valuable in those applications, thus there is always a push to achieve smaller diameters. Electrohydrodynamic (EHD) technologies have been at the forefront in the production of polymeric biomaterials, and pressurised gyration (PG) has also enhanced possibilities by its ability to spin comparable fibres at rapid speeds. In this work, PCL microparticles and fibres were separately produced by changing key operating parameters of EHD and PG systems and PCL solution properties. Initially, PCL microparticles were formed by electrospraying with different binary solvent systems, followed by pressurised gyration fibre production with various singular solvents and a pre-optimised binary solvent system. As anticipated, the use of binary systems altered particle morphologies and diameters, while increased pressure and the use of different solvents greatly affected the characteristics of resulting fibres. The morphology of PCL was found to be highly dependent on the solvents and operating parameters of the technology used.