Serum uric acid to HDL-cholesterol ratio is a strong predictor of metabolic syndrome in type 2 diabetes mellitus
Serum uric acid to HDL-cholesterol ratio is a strong predictor of metabolic syndrome in type 2 diabetes mellitus
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DOI：
10.1590/1806-9282.65.1.9
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发表时间：
2019-01-01
期刊：
影响因子：
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通讯作者：
Duman, Tuba
中科院分区：
文献类型：
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作者：
Kocak, M. Zahid;Aktas, Gulali;Duman, Tuba
目的：代谢综合征 (MS) 是一种与 2 型糖尿病 (DM) 和心血管疾病风险增加相关的临床实体。血清尿酸水平与 MS 标准相关。我们假设尿酸与 HDL-胆固醇比率 (UHR) 是否可以预测 2 型糖尿病受试者的糖尿病调节和 MS 的存在。方法：对我们机构门诊就诊的 2 型糖尿病受试者进行回顾性分析。研究人群根据 HbA1c 水平（截止值 7%）分为控制良好和控制不良的糖尿病患者，并根据是否存在 MS 进一步分为伴 MS 和不伴 MS 的 2 型 DM。比较研究组的 UHR。 结果：纳入了 100 名糖尿病受试者。与控制不佳的受试者 (14 +/- 5.4%) 相比，控制良好的糖尿病患者的平均 UHR 显着较低 (9.7 +/- 3.7%)(p
OBJECTIVE: Metabolic syndrome (MS) is a clinical entity that associated with increased risk of type 2 Diabetes Mellitus (DM) and cardiovascular diseases. Serum uric acid levels are correlated MS criteria. We hypothesized whether a uric acid to HDL-cholesterol ratio (UHR) could predict diabetic regulation and presence of MS in type 2 diabetic subjects.METHODS: Admissions of the subjects with type 2 DM to outpatient clinics of our institution were retrospectively analyzed. Study population grouped into well-controlled and poorly controlled diabetics according to the HbA1c level (cut off 7%) and further grouped into type 2 DM with and without MS according to the presence of MS. UHR of study groups compared.RESULTS: A hundred diabetic subjects enrolled. Mean UHR was significantly lower in well-controlled diabetics (9.7 +/- 3.7%) compared to poorly controlled subjects (14 +/- 5.4%)(p