An intracellular anchor regulates the distribution of bioactive molecules
An intracellular anchor regulates the distribution of bioactive molecules
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细胞内锚调节生物活性分子的分布
DOI：
10.1039/c6cc05385h
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发表时间：
2016
影响因子：
4.9
通讯作者：
Wang Shu
中科院分区：
文献类型：
--
作者：
Wang Jianwu;Li Shengliang;Chen Hui;Hu Rong;Li Meng;Lv Fengting;Liu Libing;Ma Yuguo;Wang Shu
基于生物正交四嗪连接，开发了一种预靶向锚定策略来调节生物活性分子的细胞内分布。该策略可以解决活细胞特定细胞器中生物活性分子的渗透性和靶向能力问题。
Based on bioorthogonal tetrazine ligation, a pre-targeted anchor strategy was developed to regulate the intracellular distribution of bioactive molecules. This strategy could solve the issue regarding the permeability and targeting ability of bioactive molecules in the specific organelles of living cells.