MICROTIA AND ASSOCIATED ANOMALIES - STATISTICAL-ANALYSIS

MICROTIA AND ASSOCIATED ANOMALIES - STATISTICAL-ANALYSIS
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DOI:
10.1002/ajmg.1320340424
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发表时间:
1989-12-01
期刊:
AMERICAN JOURNAL OF MEDICAL GENETICS
影响因子:
--
通讯作者:
NAGATOSHI, K
NAGATOSHI, K
中科院分区:
其他
文献类型:
--
作者:
KAYE, CI;ROLLNICK, BR;NAGATOSHI, K

文献摘要

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Terms such as oculoauriculovertebral dysplasia, Goldenhar syndrome, and hemifacial microsomia have been used to describe microtia with specific combinations of other craniofacial anomalies. Microtia is also observed with anomalies of postcranial structures. Statistical studies were performed on 297 patients with microtia and other anomalies to identify subgroups of patients representing previously described or new associations. Analysis identified 15 subgroups of patients with specific patterns of anomalies. Log-linear analyses of cranial and postcranial variables demonstrated a positive association between mandibular hypoplasia and cervical spine fusion, which was, in turn, positively associated with other spine anomalies (P