Examining inequalities in the uptake of the school-based HPV vaccination programme in England: a retrospective cohort study
Examining inequalities in the uptake of the school-based HPV vaccination programme in England: a retrospective cohort study
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DOI：
10.1093/pubmed/fdt042
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发表时间：
2014-03-01
影响因子：
4.4
通讯作者：
Trotter, Caroline
中科院分区：
文献类型：
--
作者：
Fisher, Harriet;Audrey, Suzanne;Trotter, Caroline
虽然人类乳头瘤病毒（HPV）疫苗在联合王国的使用率很高，但尚不清楚该计划是否按种族或贫困程度公平地提供。本研究旨在调查与HPV疫苗启动和完成在英格兰西南部的常规HPV疫苗接种programme中的相关因素，从2008/09年至2010/11年从三个初级保健信托基金（PCT）/地方当局检索符合常规疫苗接种条件的年轻女性的数据。在14282名符合条件的年轻女性中，12658名（88.6%）开始接种，其中11725名（92.6%）完成了接种。启动情况因方案年度（86.589.6）和方案技术小组/地方当局（84.891.6）而异。有强有力的证据表明，种族（P 0.001），但不是剥夺五分位数（P 0.48）的启动总体差异。在非主流教育环境中接受教育的年轻女性开始接种的可能性较低，如果开始接种，完成接种的可能性也较低（均P 0.001）。然而，观察到与种族和非主流教育环境中的低吸收率有关。需要进行研究，以确定这些人群中疫苗接种率低的原因。
Although uptake of Human Papillomavirus (HPV) vaccine is high in the United Kingdom, it is unknown whether the programme has been delivered equitably by ethnicity or deprivation. This study aimed to investigate factors associated with HPV vaccine initiation and completion within the routine HPV vaccination programme in the South West of England.Data were retrieved for young women eligible for routine vaccination from 2008/09 to 2010/11 from three Primary Care Trusts (PCTs)/local authorities. Multivariable logistic regression models were developed to examine factors associated with uptake of HPV vaccination.Of 14 282 eligible young women, 12 658 (88.6) initiated, of whom 11 725 (92.6) completed the course. Initiation varied by programme year (86.589.6) and PCTs/local authorities (84.891.6). There was strong evidence for an overall difference of initiation by ethnicity (P 0.001), but not deprivation quintile (P 0.48). Young women educated in non-mainstream educational settings were less likely to initiate and, if initiated, less likely to complete (both P 0.001).HPV vaccination uptake did not vary markedly by social deprivation. However, associations with ethnicity and substantially lower uptake in non-mainstream educational settings were observed. Research to identify reasons for low vaccine uptake in these population groups is required.