Innate defence of the eye by antimicrobial defensin peptides
Innate defence of the eye by antimicrobial defensin peptides
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DOI：
10.1016/s0140-6736(05)79185-6
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发表时间：
1998-08-08
期刊：
影响因子：
168.9
通讯作者：
Dua, HS
中科院分区：
文献类型：
--
作者：
Haynes, RJ;Tighe, PJ;Dua, HS
专注于在眼睛中寻找人类防御素子类。眼前泪膜的抗菌活性；防御素是一种天然存在的抗菌肽，具有抗革兰氏阳性和革兰氏阴性细菌、真菌和病毒的活性；如何使用单克隆抗体检测防御素；纯化或重组防御素用于治疗眼部感染、眼表感染和预防角膜炎。
Focuses on the search for human defensin subclasses in the eye. Antimicrobial activity of the preocular tear film; Defensin being a naturally occurring antimicrobial peptide with activity against gram-positive and gram-negative bacteria, fungi, and viruses; How a monoclonal antibody was used to detect defensins; Purified or recombinant defensins as treatment for eye infections, ocular-surface infections, and prevention of keratitis.