Novel citric acid-based biodegradable elastomers for tissue engineering
Novel citric acid-based biodegradable elastomers for tissue engineering
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DOI：
10.1002/adma.200306264
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发表时间：
2004-03-18
影响因子：
29.4
通讯作者：
Ameer, GA
中科院分区：
文献类型：
--
作者：
Yang, J;Webb, AR;Ameer, GA
报道了新型生物可降解弹性体的合成和表征，以聚（1，8-辛二醇-柠檬酸）为例。生物降解、机械和生物相容性数据表明，在心血管组织工程中用作多孔支架具有很好的潜力（见图）。材料性能可以通过调节单体比例和后聚合条件来定制。
The synthesis and characterization of novel biodegradable elastomers, exemplified by poly(1,8-octanediol-co-citric acid), is reported. Biodegradation, mechanical, and biocompatibility data suggest very good potential for use as porous scaffolds in cardiovascular tissue engineering (see Figure). Material properties can be tailored by modulating the monomer ratio and post-polymerization conditions.